Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.41 |
| ▸ | KMO | O15229 | 6/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22836610 | 1.00 | MAOB (0.45) | MAOBMAOAKDM4EALDH1A1HPGD | |
| SCHEMBL22836459 | 0.89 | MAOB (0.47) | MAOBMAOAKDM4EALDH1A1HPGD | |
| SCHEMBL29615914 | 0.89 | MAOB (0.47) | MAOBMAOAKDM4EALDH1A1HPGD | |
| SCHEMBL23529963 | 0.84 | KDM4E (0.51) | KDM4EALDH1A1HPGDPTGER4HSD17B10 | |
| SCHEMBL22222273 | 0.82 | MAOB (0.45) | MAOBMAOAALDH1A1PTGER4HCAR3 | |
| SCHEMBL22836448 | 0.74 | MAPK1 (0.43) | KDM4EALDH1A1HPGDPTGER4MAPK1 | |
| SCHEMBL29615960 | 0.74 | MAPK1 (0.43) | KDM4EALDH1A1HPGDPTGER4MAPK1 | |
| SCHEMBL24337981 | 0.73 | MAOB (0.47) | MAOBMAOAKDM4EPTGER4HSD17B10 | |
| SCHEMBL30174523 | 0.73 | MAOB (0.47) | MAOBMAOAKDM4EPTGER4HSD17B10 | |
| SCHEMBL22836543 | 0.73 | KDM4E (0.46) | KDM4EALDH1A1HPGDPTGER4HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114585609-B | 2H-indazole derivatives and their use in the treatment of diseases | 比奥根MA公司 | 2024-07-30 | — | — | CN | disclosed |
| CN-114585609-A | 2H-indazole derivatives and their use in the treatment of diseases | 比奥根MA公司 | 2022-06-03 | — | — | CN | disclosed |
| EP-3990432-A1 | 2H-INDAZOLE DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASE | Biogen MA Inc. (US) | 2022-05-04 | — | — | EP | disclosed |