Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28685857 | 1.00 | HSD11B1 (0.38) | HSD11B1KDM4EALDH1A1TSHRMAPK1 | |
| SCHEMBL18541984 | 0.79 | KDM4E (0.38) | KDM4EALDH1A1MAPTCA12CA1 | |
| SCHEMBL28679712 | 0.79 | KDM4E (0.41) | KDM4EALDH1A1MAPTCA12CA1 | |
| SCHEMBL29616354 | 0.79 | KDM4E (0.41) | KDM4EALDH1A1MAPTCA12CA1 | |
| SCHEMBL28702448 | 0.77 | CA1 (0.37) | HSD11B1KDM4EALDH1A1TSHRDPP4 | |
| SCHEMBL31406356 | 0.77 | SLC9A1 (0.43) | HSD11B1KDM4EALDH1A1TSHRDPP4 | |
| SCHEMBL13043472 | 0.77 | DPP4 (0.46) | HSD11B1KDM4EALDH1A1TSHRMAPK1 | |
| SCHEMBL13043587 | 0.75 | CA1 (0.39) | KDM4EALDH1A1TSHRHPGDMEN1 | |
| SCHEMBL2141354 | 0.74 | HTR2A (0.47) | KDM4EALDH1A1TSHRMAPK1DPP4 | |
| SCHEMBL15669103 | 0.73 | DPP4 (0.44) | KDM4EALDH1A1TSHRMAPK1DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12630510-B2 | EP2 antagonist | ONO PHARMACEUTICAL CO., LTD. (JP) | 2026-05-19 | — | — | US | disclosed |
| EP-3992176-B1 | EP2 ANTAGONIST | ONO PHARMACEUTICAL CO (JP) | 2025-08-27 | — | — | EP | disclosed |
| US-20220388955-A1 | EP2 ANTAGONIST | ONO PHARMACEUTICAL CO., LTD. (JP) | 2022-12-08 | — | — | US | disclosed |
| EP-3992176-A1 | EP2 ANTAGONIST | ONO Pharmaceutical Co., Ltd. (JP) | 2022-05-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220388955-A1 | EP2 ANTAGONIST | PTGER2, PTGER1, PTGES2 | HSD11B1 828/4885KDM4E 4168/4885ALDH1A1 1473/4885 |
| US-12630510-B2 | EP2 antagonist | PTGER2, PTGER1, PTGER4 | HSD11B1 617/4885KDM4E 3811/4885ALDH1A1 571/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.