SCHEMBL29616802

SCHEMBL29616802

CC(C)(C)OC(=O)N1CCN(c2cccc(C=O)c2)CC1

nearest known ligand 0.57

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ABCB1 P08183 3/20 0.57
GPR119 Q8TDV5 6/20 0.57
MAPT P10636 3/20 0.52
LMNA P02545 2/20 0.52
ALDH1A1 P00352 1/20 0.52
PDK2 Q15119 1/20 0.51
NAMPT P43490 1/20 0.48
HPGD P15428 1/20 0.46
JAK2 O60674 1/20 0.45
JAK3 P52333 1/20 0.45
POLB P06746 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3019659 1.00 ABCB1 (0.57) ABCB1GPR119MAPTLMNAALDH1A1
SCHEMBL25999545 0.86 ABCB1 (0.55) ABCB1GPR119MAPTLMNAALDH1A1
SCHEMBL688837 0.84 GPR119 (0.59) ABCB1GPR119MAPTLMNAALDH1A1
SCHEMBL25317395 0.84 GPR119 (0.62) ABCB1GPR119MAPTLMNAALDH1A1
SCHEMBL209802 0.84 MAPT (0.64) ABCB1GPR119MAPTLMNAALDH1A1
SCHEMBL29475574 0.84 GPR119 (0.62) ABCB1GPR119MAPTLMNAALDH1A1
SCHEMBL12082170 0.83 GPR119 (0.79) ABCB1GPR119MAPTLMNAALDH1A1
SCHEMBL30198151 0.83 GPR119 (0.60) ABCB1GPR119MAPTLMNAALDH1A1
SCHEMBL30208156 0.83 MAPT (0.63) GPR119MAPTLMNAALDH1A1
SCHEMBL1458945 0.83 MAPT (0.63) GPR119MAPTLMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119894882-A Tertiary amine compound, preparation method and medical application thereof 深圳信立泰药业股份有限公司 2025-04-25 CN disclosed
CN-116323589-A Pyridone compounds for the treatment of autoimmune diseases 豪夫迈·罗氏有限公司 2023-06-23 CN disclosed
CN-114401954-A Piperidinylamine compounds for the treatment of autoimmune diseases 豪夫迈·罗氏有限公司 2022-04-26 CN disclosed