Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.54 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.53 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.52 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.52 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.52 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.52 |
| ▸ | NAMPT | P43490 | 1/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.50 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.50 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.48 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL265132 | 1.00 | GPR119 (0.60) | GPR119MAPTALDH1A1LMNAPDK2 | |
| SCHEMBL15584576 | 0.95 | GPR119 (0.56) | GPR119MAPTALDH1A1LMNAPDK2 | |
| SCHEMBL29660540 | 0.95 | GPR119 (0.56) | GPR119MAPTALDH1A1LMNAPDK2 | |
| SCHEMBL29475574 | 0.87 | GPR119 (0.62) | GPR119MAPTALDH1A1LMNAPDK2 | |
| SCHEMBL25317395 | 0.87 | GPR119 (0.62) | GPR119MAPTALDH1A1LMNAPDK2 | |
| SCHEMBL6495092 | 0.86 | PARP14 (0.59) | GPR119MAPTALDH1A1LMNAPDK2 | |
| SCHEMBL12082170 | 0.86 | GPR119 (0.79) | GPR119MAPTALDH1A1LMNAPDK2 | |
| SCHEMBL30208161 | 0.86 | GPR119 (0.79) | GPR119MAPTALDH1A1LMNAPDK2 | |
| SCHEMBL30208156 | 0.86 | MAPT (0.63) | GPR119MAPTALDH1A1LMNA | |
| SCHEMBL1958401 | 0.86 | GPR119 (0.60) | GPR119MAPTALDH1A1LMNAPDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117586204-A | Isoseltamizolone compound, synthesis method and application thereof | 中国人民解放军海军军医大学 | 2024-02-23 | — | — | CN | disclosed |
| CN-115836056-A | NOTCH inhibitors and uses thereof | STEMSYNERGY疗法有限责任公司 | 2023-03-21 | — | — | CN | disclosed |