Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 4/20 | 0.53 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | GLS | O94925 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29616962 | 0.83 | HSP90AA1 (0.39) | ADORA2AADORA1ADORA3ADORA2BMAPT | |
| SCHEMBL29616953 | 0.82 | ADORA2A (0.44) | ADORA2AADORA1LMNAMEN1KMT2A | |
| SCHEMBL23388323 | 0.78 | ADORA2A (0.67) | ADORA2AADORA1ADORA3ADORA2BL3MBTL1 | |
| SCHEMBL29616987 | 0.75 | ADORA2A (0.47) | ADORA2AADORA1LMNAMEN1KMT2A | |
| SCHEMBL28801087 | 0.74 | ADORA2A (0.51) | ADORA2AADORA1ADORA3ADORA2BL3MBTL1 | |
| SCHEMBL1356145 | 0.74 | ADORA2A (0.44) | ADORA2AADORA1L3MBTL1LMNAMEN1 | |
| SCHEMBL1355782 | 0.73 | ADORA2A (0.43) | ADORA2AADORA1L3MBTL1LMNAMEN1 | |
| SCHEMBL1921324 | 0.70 | RECQL (0.65) | ADORA2AADORA1LMNAMEN1KMT2A | |
| SCHEMBL11002083 | 0.70 | GLS (0.67) | ADORA2AADORA1L3MBTL1LMNAMEN1 | |
| SCHEMBL31260563 | 0.70 | ADORA2A (0.61) | ADORA2AADORA1ADORA3ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022107044-A1 | PREVENTION AND/OR TREATMENT OF CNS DISORDERS | ILDONG PHARMACEUTICAL CO., LTD. (KR) | 2022-05-27 | — | — | WO | disclosed |