Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | SLC29A1 | Q99808 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | GLS | O94925 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29616953 | 0.89 | ADORA2A (0.44) | ADORA2AADORA1CYP19A1SLC29A1MEN1 | |
| SCHEMBL29616989 | 0.81 | LMNA (0.36) | SLC29A1MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL30135342 | 0.79 | RECQL (0.54) | MEN1KMT2ACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL1356145 | 0.78 | ADORA2A (0.44) | ADORA2AADORA1CYP19A1MEN1KMT2A | |
| SCHEMBL1355782 | 0.77 | ADORA2A (0.43) | ADORA2AADORA1CYP19A1MEN1KMT2A | |
| SCHEMBL30590847 | 0.76 | ADORA2A (0.45) | ADORA2AADORA1KDM4E | |
| SCHEMBL29616947 | 0.75 | ADORA2A (0.53) | ADORA2AADORA1CYP19A1MEN1KMT2A | |
| SCHEMBL1921324 | 0.74 | RECQL (0.65) | ADORA2AADORA1CYP19A1MEN1KMT2A | |
| SCHEMBL11002083 | 0.74 | GLS (0.67) | ADORA2AADORA1CYP19A1MEN1KMT2A | |
| SCHEMBL17193676 | 0.74 | ALDH1A1 (0.48) | ADORA2AADORA1GLSPOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022107044-A1 | PREVENTION AND/OR TREATMENT OF CNS DISORDERS | ILDONG PHARMACEUTICAL CO., LTD. (KR) | 2022-05-27 | — | — | WO | disclosed |