Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | SPHK2 | Q9NRA0 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.47 |
| ▸ | F10 | P00742 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.47 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.46 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.46 |
| ▸ | TGM2 | P21980 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26702822 | 0.88 | L3MBTL1 (0.70) | L3MBTL1MAPTLMNASMN1; SMN2SPHK2 | |
| SCHEMBL16858391 | 0.87 | L3MBTL1 (0.65) | L3MBTL1MAPTLMNASMN1; SMN2SPHK2 | |
| SCHEMBL3811564 | 0.87 | L3MBTL1 (0.80) | L3MBTL1MAPTLMNASMN1; SMN2HTT | |
| SCHEMBL30829569 | 0.86 | L3MBTL1 (0.64) | L3MBTL1MAPTLMNASMN1; SMN2SPHK2 | |
| SCHEMBL30829561 | 0.86 | L3MBTL1 (0.64) | L3MBTL1MAPTLMNASMN1; SMN2SPHK2 | |
| SCHEMBL29777995 | 0.85 | NR4A2 (0.64) | L3MBTL1MAPTLMNASMN1; SMN2HTT | |
| SCHEMBL30829564 | 0.85 | L3MBTL1 (0.62) | L3MBTL1MAPTLMNASMN1; SMN2SPHK2 | |
| SCHEMBL30829553 | 0.85 | L3MBTL1 (0.62) | L3MBTL1MAPTLMNASMN1; SMN2HTT | |
| SCHEMBL2572110 | 0.85 | L3MBTL1 (0.60) | L3MBTL1MAPTLMNASMN1; SMN2SPHK2 | |
| SCHEMBL23705710 | 0.84 | L3MBTL1 (0.62) | L3MBTL1MAPTLMNASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022109396-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2022-05-27 | — | — | WO | disclosed |