Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.46 |
| ▸ | LNPEP | Q9UIQ6 | 4/20 | 0.45 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | CDC25B | P30305 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | THRB | P10828 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | GFER | P55789 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PLEC | Q15149 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14876843 | 1.00 | AAK1 (0.46) | AAK1LNPEPERAP2MAPTCDC25B | |
| SCHEMBL14876842 | 0.88 | GAA (0.54) | AAK1MAPTKDM4EGAAALDH1A1 | |
| SCHEMBL3256083 | 0.86 | NPC1 (0.54) | MAPTKDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL8509027 | 0.85 | CISD2 (0.42) | AAK1MAPTKDM4EGAAALDH1A1 | |
| SCHEMBL2890796 | 0.84 | MAPT (0.46) | MAPTKDM4EGAAALDH1A1HPGD | |
| SCHEMBL30779358 | 0.84 | MAPT (0.46) | MAPTKDM4EGAAALDH1A1HPGD | |
| SCHEMBL2283371 | 0.84 | PPARG (0.51) | MAPTKDM4EGAAALDH1A1HDAC1 | |
| SCHEMBL9865843 | 0.84 | KDM5A (0.50) | MAPTKDM4EGAAALDH1A1HTT | |
| SCHEMBL2227781 | 0.83 | AAK1 (0.48) | AAK1MAPTGAAHDAC1HDAC2 | |
| SCHEMBL29741562 | 0.83 | HPGD (0.49) | AAK1HPGDHDAC1SMN1; SMN2HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108201625-B | Linker drugs and antibody drug complexes comprising the same | 财团法人工业技术研究院 | 2022-06-07 | — | — | CN | disclosed |