SCHEMBL29617539

SCHEMBL29617539

CCCC(CCC)C(=O)OC(=O)/C=C/C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 10/20 0.53
HDAC1 Q13547 2/20 0.43
HDAC2 Q92769 2/20 0.43
CHRM1 P11229 2/20 0.43
CHRM3 P20309 2/20 0.43
ADRA1A P35348 2/20 0.43
AKR1A1 P14550 1/20 0.43
HTR2A P28223 1/20 0.43
HTR2C P28335 1/20 0.43
HRH1 P35367 1/20 0.43
DRD3 P35462 1/20 0.43
SLC6A3 Q01959 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
ATM Q13315 1/20 0.38
TSHR P16473 3/20 0.38
CYP3A4 P08684 2/20 0.38
NFKB1 P19838 2/20 0.38
NPSR1 Q6W5P4 2/20 0.38
HDAC7 Q8WUI4 2/20 0.37
HDAC8 Q9BY41 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28413287 0.92 HDAC1 (0.44) HCAR2HDAC1HDAC2CHRM1CHRM3
SCHEMBL4447846 0.89 HCAR2 (0.56) HCAR2ATMTSHRSLC1A3SLC1A2
SCHEMBL4447841 0.89 HCAR2 (0.56) HCAR2ATMTSHRSLC1A3SLC1A2
SCHEMBL4447838 0.81 CA2 (0.50) HCAR2TDP1ATMTSHRCYP3A4
SCHEMBL358441 0.77 HDAC1 (0.55) HDAC1HDAC2CHRM1CHRM3ADRA1A
SCHEMBL11851897 0.76 HCAR2 (0.47) HCAR2HDAC1HDAC2CHRM1CHRM3
SCHEMBL15605564 0.76 HDAC1 (0.54) HDAC1HDAC2CHRM1CHRM3ADRA1A
Valproic Acid SCHEMBL28413291 0.76 CHRM1 (0.76) HCAR2HDAC1HDAC2CHRM1CHRM3
SCHEMBL27500646 0.75 HDAC1 (0.52) HDAC1HDAC2CHRM1CHRM3ADRA1A
SCHEMBL11851327 0.75 HCAR2 (0.57) HCAR2ATMACHEBACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114632073-A Propofol fumarate and tenofovir oral instant film agent and preparation method thereof 南京海辰药业股份有限公司 2022-06-17 CN disclosed