SCHEMBL4447846

SCHEMBL4447846

CCCCC(CCCC)C(=O)OC(=O)C=CC(=O)O

nearest known ligand 0.56

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 7/20 0.56
CA2 P00918 3/20 0.44
CA1 P00915 2/20 0.44
ATM Q13315 1/20 0.44
MAPK1 P28482 1/20 0.44
ACHE P22303 1/20 0.44
BACE1 P56817 1/20 0.44
TSHR P16473 1/20 0.41
SLC1A3 P43003 1/20 0.39
SLC1A2 P43004 1/20 0.39
SLC1A1 P43005 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4447841 1.00 HCAR2 (0.56) HCAR2CA2CA1ATMMAPK1
SCHEMBL4447838 0.93 CA2 (0.50) HCAR2CA2CA1ATMMAPK1
SCHEMBL29617539 0.89 HCAR2 (0.53) HCAR2ATMACHEBACE1TSHR
SCHEMBL28413287 0.81 HDAC1 (0.44) HCAR2CA2CA1ATMTSHR
SCHEMBL11851327 0.79 HCAR2 (0.57) HCAR2ATMACHEBACE1
SCHEMBL27569057 0.78 TSHR (0.63) HCAR2CA2ATMMAPK1ACHE
Maleic Acid SCHEMBL28967009 0.77 HCAR2 (0.58) HCAR2CA2CA1ATMMAPK1
SCHEMBL790118 0.75 TSHR (0.69) HCAR2CA2ATMMAPK1ACHE
SCHEMBL8461085 0.75 HCAR2 (0.59) HCAR2ATMACHEBACE1TSHR
SCHEMBL972676 0.75 TSHR (0.69) HCAR2CA2ATMMAPK1ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1773937-A4 PROCESSING AID FOR PVC AND METHOD FOR MANUFACTURING THE SAME LG CHEMICAL LTD (KR) 2009-01-14 EP claimed
US-20080139713-A1 A methyl methacrylate copolymer plasticizer or internal lubricant; microemulsification with a ultrahydrophobe, a plasticizer or an internal lubricant, an emulsifier, and an initiator; emulsion copolymerization, spray drying; increased melt speed and processability LG CHEM, LTD. (KR) 2008-06-12 US claimed
EP-1773937-A1 PROCESSING AID FOR PVC AND METHOD FOR MANUFACTURING THE SAME LG Chem, Ltd. (KR) 2007-04-18 EP claimed
WO-2006062366-A1 PROCESSING AID FOR PVC AND METHOD FOR MANUFACTURING THE SAME LG CHEM, LTD. (KR) 2006-06-15 WO claimed
EP-1773937-A4 PROCESSING AID FOR PVC AND METHOD FOR MANUFACTURING THE SAME LG CHEMICAL LTD (KR) 2009-01-14 EP disclosed
US-20080139713-A1 A methyl methacrylate copolymer plasticizer or internal lubricant; microemulsification with a ultrahydrophobe, a plasticizer or an internal lubricant, an emulsifier, and an initiator; emulsion copolymerization, spray drying; increased melt speed and processability LG CHEM, LTD. (KR) 2008-06-12 US disclosed
EP-1773937-A1 PROCESSING AID FOR PVC AND METHOD FOR MANUFACTURING THE SAME LG Chem, Ltd. (KR) 2007-04-18 EP disclosed
WO-2006062366-A1 PROCESSING AID FOR PVC AND METHOD FOR MANUFACTURING THE SAME LG CHEM, LTD. (KR) 2006-06-15 WO disclosed