Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.54 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.54 |
| ▸ | IKBKB | O14920 | 3/20 | 0.51 |
| ▸ | CHUK | O15111 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CLK1 | P49759 | 1/20 | 0.46 |
| ▸ | CLK2 | P49760 | 1/20 | 0.46 |
| ▸ | CLK3 | P49761 | 1/20 | 0.46 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.46 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3966553 | 1.00 | SIRT3 (0.59) | SIRT3TDP1MKNK1MKNK2IKBKB | |
| Hydrochloric Acid SCHEMBL31208514 | 0.98 | SIRT3 (0.58) | SIRT3TDP1MKNK1MKNK2IKBKB | |
| Formic Acid SCHEMBL9954311 | 0.93 | SIRT3 (0.53) | SIRT3TDP1MKNK1MKNK2IKBKB | |
| SCHEMBL15664780 | 0.88 | SIRT3 (0.54) | SIRT3TDP1MKNK1MKNK2IKBKB | |
| SCHEMBL27569244 | 0.87 | HTT (0.55) | SIRT3TDP1MKNK1MKNK2IKBKB | |
| SCHEMBL607011 | 0.85 | MKNK1 (0.57) | SIRT3TDP1MKNK1MKNK2IKBKB | |
| Salicylic Acid SCHEMBL31026153 | 0.84 | ALDH1A1 (0.47) | SIRT3TDP1MKNK1MKNK2IKBKB | |
| SCHEMBL668446 | 0.83 | KDM4C (0.49) | SIRT3TDP1CA12CA1CA2 | |
| SCHEMBL30465506 | 0.83 | KDM4C (0.49) | SIRT3TDP1CA12CA1CA2 | |
| SCHEMBL334854 | 0.83 | CA12 (0.47) | SIRT3TDP1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4448510-A1 | INHIBITORS OF MET KINASE | Kinnate Biopharma Inc. (US) | 2024-10-23 | — | — | EP | disclosed |
| WO-2023114809-A1 | INHIBITORS OF MET KINASE | KINNATE BIOPHARMA INC. (US) | 2023-06-22 | — | — | WO | disclosed |
| CN-114685516-A | Pyrazolopyrimidine derivatives as BTK inhibitors for the treatment of cancer | 洛克索肿瘤学股份有限公司 | 2022-07-01 | — | — | CN | disclosed |
| CN-108431007-B | Pyrazolopyrimidine derivatives as BTK inhibitors for the treatment of cancer | 洛克索肿瘤学股份有限公司 | 2022-06-07 | — | — | CN | disclosed |