Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.36 |
| ▸ | PDE2A | O00408 | 2/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19816520 | 1.00 | HTT (0.45) | HTTLMNATP53CXCR3MDM2 | |
| SCHEMBL84107 | 0.84 | LMNA (0.47) | HTTLMNATP53CXCR3MDM2 | |
| SCHEMBL30399466 | 0.81 | PDE2A (0.46) | HTTLMNATP53CXCR3MDM2 | |
| SCHEMBL2295810 | 0.81 | PDE2A (0.46) | HTTLMNATP53CXCR3MDM2 | |
| SCHEMBL29924355 | 0.81 | PDE2A (0.46) | HTTLMNATP53CXCR3MDM2 | |
| SCHEMBL13778123 | 0.81 | LMNA (0.64) | HTTLMNATP53CXCR3MDM2 | |
| SCHEMBL16046022 | 0.81 | LMNA (0.64) | HTTLMNATP53CXCR3MDM2 | |
| SCHEMBL8284264 | 0.81 | LMNA (0.64) | HTTLMNATP53CXCR3MDM2 | |
| SCHEMBL17553254 | 0.81 | LMNA (0.44) | HTTLMNATP53CXCR3MDM2 | |
| SCHEMBL17215353 | 0.81 | PDE2A (0.46) | HTTLMNATP53CXCR3MDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114591308-B | GLP-1R receptor agonist compounds and application thereof | 苏州闻泰医药科技有限公司 | 2024-03-08 | — | — | CN | disclosed |
| CN-109789146-B | Chemokine receptor modulators and uses thereof | 拉普特医疗公司 | 2023-04-18 | — | — | CN | disclosed |
| CN-114591308-A | GLP-1R receptor agonist compounds and application thereof | 苏州闻泰医药科技有限公司 | 2022-06-07 | — | — | CN | disclosed |