Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24517473 | 1.00 | KDM4E (0.40) | KDM4EALDH1A1GAAADORA1HSD17B10 | |
| SCHEMBL29618403 | 0.80 | SMN1; SMN2 (0.53) | KDM4EALDH1A1GAAHSD17B10TSHR | |
| SCHEMBL28758443 | 0.80 | SMN1; SMN2 (0.53) | KDM4EALDH1A1GAAHSD17B10TSHR | |
| SCHEMBL24517534 | 0.80 | KDM4E (0.36) | KDM4EALDH1A1GAAHSD17B10TSHR | |
| SCHEMBL29618381 | 0.74 | DYRK1A (0.36) | ALDH1A1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL21935992 | 0.74 | DYRK1A (0.36) | ALDH1A1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31168552 | 0.74 | DYRK1A (0.36) | ALDH1A1NPC1RAB9ASMN1; SMN2DYRK1A | |
| SCHEMBL31168524 | 0.74 | DYRK1A (0.36) | GAARAB9ASMN1; SMN2DYRK1A | |
| SCHEMBL24517477 | 0.71 | ALDH1A1 (0.41) | KDM4EALDH1A1GAAADORA1HSD17B10 | |
| SCHEMBL29664483 | 0.71 | ALDH1A1 (0.41) | KDM4EALDH1A1GAAADORA1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022121805-A1 | FUSED RING COMPOUND AS NAV1.8 INHIBITOR AND USE THEREOF | 成都康弘药业集团股份有限公司 | 2022-06-16 | — | — | WO | disclosed |
| CN-114591293-A | Fused ring compound as Nav1.8 inhibitor and application thereof | 成都康弘药业集团股份有限公司 | 2022-06-07 | — | — | CN | disclosed |