Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA7 | P43166 | 2/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1506551 | 1.00 | ALDH1A1 (0.48) | ALDH1A1KDM4EMEN1GAAMAPT | |
| SCHEMBL11980453 | 0.95 | MEN1 (0.54) | ALDH1A1KDM4EMEN1GAAMAPT | |
| SCHEMBL19996819 | 0.93 | MEN1 (0.52) | ALDH1A1KDM4EMEN1GAAMAPT | |
| SCHEMBL24377317 | 0.93 | MEN1 (0.52) | ALDH1A1KDM4EMEN1GAAMAPT | |
| SCHEMBL30811423 | 0.90 | KDM4E (0.41) | ALDH1A1KDM4EMEN1GAAMAPT | |
| SCHEMBL25001630 | 0.90 | KDM4E (0.41) | ALDH1A1KDM4EMEN1GAAMAPT | |
| SCHEMBL5837186 | 0.81 | KMT2A (0.59) | ALDH1A1KDM4EMEN1GAAMAPT | |
| SCHEMBL3519553 | 0.81 | GRIN2D (0.40) | ALDH1A1KDM4EMEN1GAAMAPT | |
| SCHEMBL30311025 | 0.78 | PRKCG (0.31) | — | |
| SCHEMBL1506627 | 0.78 | PRKCG (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114591293-A | Fused ring compound as Nav1.8 inhibitor and application thereof | 成都康弘药业集团股份有限公司 | 2022-06-07 | — | — | CN | disclosed |