Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 18/20 | 0.85 |
| ▸ | PRKCA | P17252 | 10/20 | 0.85 |
| ▸ | PRKCD | Q05655 | 7/20 | 0.85 |
| ▸ | EGFR | P00533 | 3/20 | 0.85 |
| ▸ | BCR | P11274 | 16/20 | 0.72 |
| ▸ | SRC | P12931 | 9/20 | 0.72 |
| ▸ | PRKACA | P17612 | 1/20 | 0.72 |
| ▸ | PRKACG | P22612 | 1/20 | 0.72 |
| ▸ | PRKACB | P22694 | 1/20 | 0.72 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.64 |
| ▸ | PRKCG | P05129 | 2/20 | 0.64 |
| ▸ | PRKCB | P05771 | 2/20 | 0.64 |
| ▸ | PRKCH | P24723 | 2/20 | 0.64 |
| ▸ | PRKCI | P41743 | 2/20 | 0.64 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.64 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.64 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.64 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.64 |
| ▸ | LCK | P06239 | 1/20 | 0.64 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6262145 | 0.92 | ABL1 (1.00) | ABL1PRKCAPRKCDEGFRBCR | |
| Phosphoric Acid SCHEMBL7471510 | 0.86 | ABL1 (0.86) | ABL1PRKCAPRKCDEGFRBCR | |
| SCHEMBL16932355 | 0.85 | ABL1 (0.76) | ABL1PRKCAPRKCDEGFRBCR | |
| SCHEMBL7476133 | 0.85 | ABL1 (0.76) | ABL1PRKCAPRKCDEGFRBCR | |
| SCHEMBL7464205 | 0.85 | ABL1 (0.76) | ABL1PRKCAPRKCDEGFRBCR | |
| SCHEMBL7461475 | 0.85 | ABL1 (0.76) | ABL1PRKCAPRKCDEGFRBCR | |
| SCHEMBL3868291 | 0.85 | ABL1 (0.76) | ABL1PRKCAPRKCDEGFRBCR | |
| SCHEMBL7461678 | 0.84 | ABL1 (0.73) | ABL1PRKCAPRKCDEGFRBCR | |
| SCHEMBL1465 | 0.84 | ABL1 (1.00) | ABL1PRKCAPRKCDEGFRBCR | |
| SCHEMBL6859862 | 0.84 | ABL1 (0.71) | ABL1PRKCAPRKCDEGFRBCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114502555-A | Derivatives of 4- (imidazo [1,2-a ] pyridin-3-yl) -N- (pyridin-3-yl) pyrimidin-2-amines for the treatment of proliferative diseases and disorders | 常州千红生化制药股份有限公司 | 2022-05-13 | — | — | CN | disclosed |