Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 5/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21001639 | 1.00 | MAPT (0.39) | MAPTGLATSHRLMNAHTT | |
| SCHEMBL20906675 | 0.79 | GAA (0.37) | TSHRLMNAMEN1KMT2ACYP2D6 | |
| SCHEMBL18622635 | 0.77 | ALDH1A1 (0.35) | MAPTLMNAMEN1KMT2APOLB | |
| SCHEMBL20906749 | 0.77 | MCL1 (0.40) | HTTKMT2AHPGDKDM4E | |
| SCHEMBL22379888 | 0.75 | KDM4E (0.41) | MAPTLMNAHTTMEN1KMT2A | |
| SCHEMBL17281890 | 0.74 | ALDH1A1 (0.49) | GLANPSR1GAAKDM4ECYP1A2 | |
| SCHEMBL25836799 | 0.74 | HTR1A (0.41) | MAPTLMNAMEN1KMT2APOLB | |
| SCHEMBL10504348 | 0.73 | AKR1B1 (0.41) | MAPTGLATSHRLMNAMEN1 | |
| SCHEMBL24982920 | 0.72 | ALDH1A1 (0.40) | MAPTLMNAMEN1KMT2ACYP2D6 | |
| SCHEMBL21001297 | 0.72 | ALDH1A1 (0.41) | MAPTGLATSHRLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111372923-B | 1, 3-dipolar compounds comprising epoxy groups | 米其林集团总公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-111372790-B | Diene polymers modified by epoxide groups | 米其林集团总公司 | 2022-06-21 | — | — | CN | disclosed |
| CN-111356596-B | Rubber composition | 米其林集团总公司 | 2022-06-21 | — | — | CN | disclosed |