Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | GHSR | Q92847 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NMBR | P28336 | 1/20 | 0.30 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24461333 | 1.00 | TACR1 (0.38) | TACR1GHSRLMNAKMT2ANMBR | |
| SCHEMBL29619440 | 0.83 | SMARCA2 (0.38) | TACR1GHSRNMBR | |
| SCHEMBL24461521 | 0.83 | SMARCA2 (0.38) | TACR1GHSRNMBR | |
| SCHEMBL17999311 | 0.78 | TACR1 (0.43) | TACR1GHSRLMNANMBR | |
| SCHEMBL17999310 | 0.78 | TACR1 (0.43) | TACR1GHSRLMNANMBR | |
| SCHEMBL31424848 | 0.71 | ESR2 (0.40) | LMNAKMT2A | |
| SCHEMBL24461199 | 0.71 | MKNK1 (0.36) | LMNAKMT2A | |
| SCHEMBL30552452 | 0.70 | LMNA (0.44) | LMNAKMT2A | |
| SCHEMBL5881032 | 0.70 | TACR1 (0.51) | TACR1GHSRLMNAKMT2ANMBR | |
| SCHEMBL17999521 | 0.70 | F9 (0.42) | TACR1GHSRLMNAKMT2ANMBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022109426-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2022-05-27 | — | — | WO | disclosed |