Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 9/20 | 0.58 |
| ▸ | NPY1R | P25929 | 6/20 | 0.58 |
| ▸ | NPY2R | P49146 | 4/20 | 0.58 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.58 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.57 |
| ▸ | DRD1 | P21728 | 1/20 | 0.57 |
| ▸ | GNRHR | P30968 | 1/20 | 0.57 |
| ▸ | MRGPRX2 | Q96LB1 | 1/20 | 0.57 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.54 |
| ▸ | NMUR2 | Q9GZQ4 | 2/20 | 0.53 |
| ▸ | NMUR1 | Q9HB89 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29390426 | 0.92 | OPRM1 (0.61) | NPY4RNPY1RNPY2RNPY5ROPRM1 | |
| SCHEMBL5499951 | 0.90 | NPY4R (0.58) | NPY4RNPY1RNPY2RNPY5RNMUR2 | |
| SCHEMBL8019005 | 0.89 | OPRM1 (0.60) | NPY4RNPY1RNPY2RNPY5ROPRM1 | |
| SCHEMBL30585577 | 0.89 | OPRM1 (0.48) | NPY4RNPY1RNPY2RNPY5ROPRM1 | |
| SCHEMBL30422214 | 0.88 | OPRD1 (0.55) | NPY4RNPY1RNPY2RNPY5ROPRM1 | |
| SCHEMBL30943512 | 0.88 | NTSR2 (0.56) | NPY4RNPY1RNPY2RNPY5ROPRM1 | |
| Hydrochloric Acid SCHEMBL11665303 | 0.87 | NMUR2 (0.58) | NPY4RNPY1RNPY2RNPY5ROPRM1 | |
| SCHEMBL8808113 | 0.87 | NMUR2 (0.70) | OPRM1OPRK1NMUR2NMUR1 | |
| SCHEMBL8808129 | 0.87 | NMUR2 (0.70) | OPRM1OPRK1NMUR2NMUR1 | |
| SCHEMBL10588690 | 0.86 | NPY4R (0.61) | NPY4RNPY1RNPY2RNPY5RNMUR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4237012-A1 | FAP-ACTIVATED SERUM EXTENDED HALF-LIFE THERAPEUTIC CONJUGATES | Avacta Life Sciences Limited (GB) | 2023-09-06 | — | — | EP | disclosed |
| WO-2022094262-A1 | FAP-ACTIVATED SERUM EXTENDED HALF-LIFE THERAPEUTIC CONJUGATES | AVACTA LIFE SCIENCES LIMITED (GB) | 2022-05-05 | — | — | WO | disclosed |