Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 3/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | CA4 | P22748 | 3/20 | 0.47 |
| ▸ | CA7 | P43166 | 3/20 | 0.47 |
| ▸ | CA9 | Q16790 | 3/20 | 0.47 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HMGB1 | P09429 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.46 |
| ▸ | GGT1 | P19440 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2559743 | 1.00 | FOLH1 (0.55) | FOLH1ALDH1A1ALOX15L3MBTL1TSHR | |
| Chloroform SCHEMBL6799813 | 0.93 | FOLH1 (0.49) | FOLH1ALDH1A1ALOX15L3MBTL1TSHR | |
| SCHEMBL8208884 | 0.85 | L3MBTL1 (0.49) | FOLH1ALDH1A1L3MBTL1TSHRKDM4E | |
| Benzene SCHEMBL10992898 | 0.84 | L3MBTL1 (0.60) | ALDH1A1L3MBTL1NAPRTHSD17B10TDP1 | |
| SCHEMBL3969116 | 0.84 | FOLH1 (0.52) | FOLH1ALDH1A1ALOX15TSHRCA12 | |
| SCHEMBL28341137 | 0.84 | L3MBTL1 (0.49) | FOLH1ALDH1A1ALOX15L3MBTL1TSHR | |
| SCHEMBL6530167 | 0.83 | FOLH1 (0.59) | FOLH1ALDH1A1ALOX15TSHRCA12 | |
| 2-Carboxybenzeneacetic Acid SCHEMBL1891118 | 0.83 | AKR1B1 (0.61) | FOLH1ALDH1A1ALOX15TSHRCA12 | |
| 2-Carboxybenzeneacetic Acid SCHEMBL27477 | 0.83 | AKR1B1 (0.61) | FOLH1ALDH1A1ALOX15TSHRCA12 | |
| SCHEMBL28853970 | 0.82 | FOLH1 (0.49) | FOLH1ALDH1A1ALOX15L3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114181201-B | Novel compounds as potential therapeutic agents against various neurodegenerative diseases | 香港科技大学 | 2023-12-01 | — | — | CN | disclosed |
| CN-114181201-A | Novel compounds as potential therapeutic agents against various neurodegenerative diseases | 香港科技大学 | 2022-03-15 | — | — | CN | disclosed |