Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.50 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.46 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.43 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.41 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 4/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.39 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.37 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24654245 | 1.00 | HTR2A (0.52) | HTR2AMAPTSMN1; SMN2NPSR1SOS2 | |
| SCHEMBL22879439 | 0.82 | HTR2A (0.58) | HTR2AMAPTSMN1; SMN2NPSR1SOS2 | |
| SCHEMBL13715290 | 0.82 | HTR2A (0.61) | HTR2AMAPTSMN1; SMN2NPSR1SOS2 | |
| SCHEMBL24654093 | 0.77 | MEN1 (0.55) | HTR2AMAPTSMN1; SMN2POLBGPR84 | |
| SCHEMBL27911678 | 0.74 | HTR2A (0.69) | HTR2AMAPTSMN1; SMN2NPSR1SOS2 | |
| SCHEMBL28114102 | 0.74 | MEN1 (0.44) | SMN1; SMN2NR3C2 | |
| SCHEMBL23360640 | 0.74 | HTR2A (0.55) | HTR2AMAPTSMN1; SMN2NPSR1SOS2 | |
| SCHEMBL24654244 | 0.73 | HTR2A (0.51) | HTR2AMAPTSMN1; SMN2NPSR1PCSK9 | |
| SCHEMBL8297888 | 0.73 | HTR2A (0.67) | HTR2AMAPTSMN1; SMN2NPSR1SOS2 | |
| SCHEMBL6284097 | 0.73 | HTR2A (0.58) | HTR2AMAPTSMN1; SMN2NPSR1SOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022082817-A1 | 3-THREE-MEMBERED SPIROOXINDOLE DERIVATIVE SYNTHESIZING METHOD | 苏州大学 | 2022-04-28 | — | — | WO | disclosed |