Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.55 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.51 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.49 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.49 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3611008 | 0.86 | HTR2A (0.60) | HTR2AMAPTSMN1; SMN2NPSR1BRPF1 | |
| SCHEMBL5694492 | 0.85 | TDP1 (0.53) | MAPTSMN1; SMN2NPSR1KDM4EMEN1 | |
| SCHEMBL24814480 | 0.84 | SOS2 (0.60) | HTR2AMAPTSMN1; SMN2NPSR1BRPF1 | |
| SCHEMBL10678420 | 0.84 | HTR2A (0.63) | HTR2AMAPTSMN1; SMN2NPSR1BRPF1 | |
| SCHEMBL6131640 | 0.84 | ALDH1A1 (0.57) | MAPTSMN1; SMN2NPSR1KDM4EMEN1 | |
| SCHEMBL17102847 | 0.83 | ALDH1A1 (0.59) | MAPTSMN1; SMN2NPSR1KDM4EMEN1 | |
| SCHEMBL5058671 | 0.82 | ALDH1A1 (0.46) | MAPTSMN1; SMN2NPSR1KDM4EMEN1 | |
| SCHEMBL21808837 | 0.82 | PKM (0.66) | HTR2AMAPTSMN1; SMN2NPSR1BRPF1 | |
| SCHEMBL23360640 | 0.81 | HTR2A (0.55) | HTR2AMAPTSMN1; SMN2NPSR1BRPF1 | |
| SCHEMBL8297888 | 0.81 | HTR2A (0.67) | HTR2AMAPTSMN1; SMN2NPSR1BRPF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119332255-A | Electrochemical synthesis method of arundone derivatives | 云南师范大学 | 2025-01-21 | — | — | CN | claimed |
| CN-117946367-A | Preparation method of water-based polyurethane leather coating containing natural antibacterial factors | 四川大学 | 2024-04-30 | — | — | CN | claimed |
| EP-3636642-B1 | INDOLEACETIC ACID DERIVATIVES FOR USE IN THE TREATMENT OF COUGH | INST CHINESE MATERIA MEDICA CHINA ACADEMY OF CMS (CN) | 2025-12-24 | — | — | EP | disclosed |
| CN-119332255-A | Electrochemical synthesis method of arundone derivatives | 云南师范大学 | 2025-01-21 | — | — | CN | disclosed |
| CN-119307565-A | Method for synthesizing L-7-methyl tryptophan by enzyme method | 浙江普洛生物科技有限公司 | 2025-01-14 | — | — | CN | disclosed |
| CN-117946367-A | Preparation method of water-based polyurethane leather coating containing natural antibacterial factors | 四川大学 | 2024-04-30 | — | — | CN | disclosed |
| US-11008360-B2 | Indoleacetic acid derivative and preparation method and pharmaceutical use thereof | INSTITUTE OF CHINESE MATERIA MEDICA, CHINA ACADEMY OF CHINESE MEDICAL SCIENCES (CN) | 2021-05-18 | — | — | US | disclosed |
| US-11008360-B2 | Indoleacetic acid derivative and preparation method and pharmaceutical use thereof | INSTITUTE OF CHINESE MATERIA MEDICA, CHINA ACADEMY OF CHINESE MEDICAL SCIENCES (CN) | 2021-05-18 | — | — | US | disclosed |
| EP-3636642-A1 | INDOLEACETIC ACID DERIVATIVE AND PREPARATION METHOD AND PHARMACEUTICAL USE THEREOF | Institute Of Chinese Materia Medica China Academy of Sciences (CN) | 2020-04-15 | — | — | EP | disclosed |
| EP-3636642-A1 | INDOLEACETIC ACID DERIVATIVE AND PREPARATION METHOD AND PHARMACEUTICAL USE THEREOF | Institute Of Chinese Materia Medica China Academy of Sciences (CN) | 2020-04-15 | — | — | EP | disclosed |
| US-20200095271-A1 | INDOLEACETIC ACID DERIVATIVE AND PREPARATION METHOD AND PHARMACEUTICAL USE THEREOF | INSTITUTE OF CHINESE MATERIA MEDICA, CHINA ACADEMY OF CHINESE MEDICAL SCIENCES (CN) | 2020-03-26 | — | — | US | disclosed |
| US-20200095271-A1 | INDOLEACETIC ACID DERIVATIVE AND PREPARATION METHOD AND PHARMACEUTICAL USE THEREOF | INSTITUTE OF CHINESE MATERIA MEDICA, CHINA ACADEMY OF CHINESE MEDICAL SCIENCES (CN) | 2020-03-26 | — | — | US | disclosed |
| CN-103347874-B | dimeric IAP inhibitors | NOVARTIS AG (CH) | 2014-10-29 | — | — | CN | disclosed |
| CN-103347874-A | Dimeric iap inhibitors | NOVARTIS AG | 2013-10-09 | — | — | CN | disclosed |
| CN-102770425-A | Indolyl-piperidinylbenzylamines as beta-tryptase inhibitors | SANOFI SA | 2012-11-07 | — | — | CN | disclosed |
| US-6887890-B2 | Compounds exhibiting thrombopoietin-like activities | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2005-05-03 | — | — | US | disclosed |
| US-20030162724-A1 | Compounds exhibiting thrombopoietin-like activities | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2003-08-28 | — | — | US | disclosed |
| EP-1291341-A1 | COMPOUNDS EXHIBITING THROMBOPOIETIN-LIKE ACTIVITIES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2003-03-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200095271-A1 | INDOLEACETIC ACID DERIVATIVE AND PREPARATION METHOD AND PHARMACEUTICAL USE THEREOF | IDO1, IDO2, TPH1 | HTR2A 18/4885MAPT 1307/4885SMN1; SMN2 4038/4885 |
| US-11008360-B2 | Indoleacetic acid derivative and preparation method and pharmaceutical use thereof | IDO1, IDO2, TPH1 | HTR2A 18/4885MAPT 1307/4885SMN1; SMN2 4038/4885 |
| US-20030162724-A1 | Compounds exhibiting thrombopoietin-like activities | MPL, THPO, TEK | HTR2A 799/4885MAPT 4866/4885SMN1; SMN2 1648/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.