Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.53 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.52 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.47 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.46 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3279608 | 0.90 | BRPF1 (0.55) | HTR2AMAPTSMN1; SMN2NPSR1BRPF1 | |
| SCHEMBL23370445 | 0.83 | NR4A2 (0.48) | HTR2AMAPTSMN1; SMN2NPSR1BRPF1 | |
| SCHEMBL6284097 | 0.81 | HTR2A (0.58) | HTR2AMAPTSMN1; SMN2NPSR1BRPF1 | |
| SCHEMBL21392080 | 0.81 | CHRNB2 (0.47) | SMN1; SMN2HTTMTNR1AMTNR1BCNR2 | |
| SCHEMBL10678420 | 0.79 | HTR2A (0.63) | HTR2AMAPTSMN1; SMN2NPSR1BRPF1 | |
| SCHEMBL8297888 | 0.79 | HTR2A (0.67) | HTR2AMAPTSMN1; SMN2NPSR1BRPF1 | |
| SCHEMBL6920054 | 0.78 | MTNR1A (0.70) | HTR2AMAPTSMN1; SMN2NPSR1BRPF1 | |
| SCHEMBL3611008 | 0.77 | HTR2A (0.60) | HTR2AMAPTSMN1; SMN2NPSR1BRPF1 | |
| SCHEMBL27911678 | 0.77 | HTR2A (0.69) | HTR2AMAPTSMN1; SMN2NPSR1BRPF1 | |
| SCHEMBL24328921 | 0.77 | SMN1; SMN2 (0.61) | HTR2AMAPTSMN1; SMN2NPSR1BRPF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210147405-A1 | BICYCLIC HETEROAROMATIC UREA OR CARBAMATE COMPOUNDS FOR USE IN THERAPY | EUROPEAN MOLECULAR BIOLOGY LABORATORY (DE) | 2021-05-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210147405-A1 | BICYCLIC HETEROAROMATIC UREA OR CARBAMATE COMPOUNDS FOR USE IN THERAPY | HIF1A, HIF1AN, EGLN3 | HTR2A 3750/4885MAPT 1519/4885SMN1; SMN2 4652/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.