Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 17/20 | 0.50 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | FAP | Q12884 | 1/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29619666 | 0.87 | DPP4 (0.49) | DPP4DPP7KCNH2DPP9 | |
| SCHEMBL29619670 | 0.79 | DPP4 (0.49) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL28261299 | 0.75 | DPP4 (0.47) | DPP4DPP7FAPDPP8DPP9 | |
| SCHEMBL1644939 | 0.71 | PTGS2 (0.34) | DPP4DPP9 | |
| SCHEMBL1644938 | 0.71 | PTGS2 (0.34) | DPP4DPP9 | |
| SCHEMBL28680670 | 0.70 | DPP4 (0.55) | DPP4DPP7FAPDPP8DPP9 | |
| SCHEMBL743075 | 0.70 | DPP4 (0.64) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL28183038 | 0.69 | DPP4 (0.45) | DPP4DPP7FAPDPP8DPP9 | |
| SCHEMBL31225236 | 0.68 | DPP4 (0.49) | DPP4DPP7FAPDPP8DPP9 | |
| SCHEMBL13005317 | 0.67 | DPP4 (0.56) | DPP4DPP7FAPDPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022088528-A1 | TRANSAMINASE MUTANT AND USE THEREOF IN PREPARATION OF SITAGLIPTIN INTERMEDIATE | 浙江永太科技股份有限公司 | 2022-05-05 | — | — | WO | disclosed |