Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 17/20 | 0.49 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29619675 | 0.87 | DPP4 (0.50) | DPP4DPP9KCNH2DPP7 | |
| SCHEMBL1644938 | 0.81 | PTGS2 (0.34) | DPP4DPP9RORC | |
| SCHEMBL1644939 | 0.81 | PTGS2 (0.34) | DPP4DPP9RORC | |
| SCHEMBL29619670 | 0.81 | DPP4 (0.49) | DPP4DPP9DPP7 | |
| SCHEMBL332351 | 0.76 | ALDH1A1 (0.46) | DPP4DPP9KCNH2 | |
| SCHEMBL28973626 | 0.74 | DPP4 (0.42) | DPP4DPP9KCNH2 | |
| SCHEMBL1644943 | 0.73 | DPP4 (0.51) | DPP4DPP9DPP7 | |
| SCHEMBL3992304 | 0.73 | DPP4 (0.51) | DPP4DPP9DPP7 | |
| SCHEMBL3985105 | 0.73 | DPP4 (0.51) | DPP4DPP9DPP7 | |
| SCHEMBL25663565 | 0.73 | DPP4 (0.51) | DPP4DPP9DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022088528-A1 | TRANSAMINASE MUTANT AND USE THEREOF IN PREPARATION OF SITAGLIPTIN INTERMEDIATE | 浙江永太科技股份有限公司 | 2022-05-05 | — | — | WO | disclosed |