Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.50 |
| ▸ | CTSB | P07858 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | GPR35 | Q9HC97 | 5/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | CASP6 | P55212 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.43 |
| ▸ | ABAT | P80404 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25223930 | 1.00 | HPGD (0.50) | HPGDSMN1; SMN2TP53TSHRHIF1A | |
| SCHEMBL4582709 | 0.85 | SMN1; SMN2 (0.52) | HPGDSMN1; SMN2TP53TSHRHIF1A | |
| SCHEMBL1063867 | 0.83 | GPR35 (0.48) | HPGDSMN1; SMN2TP53TSHRHIF1A | |
| SCHEMBL11416696 | 0.82 | GPR35 (0.55) | HPGDSMN1; SMN2TP53TSHRHIF1A | |
| SCHEMBL351534 | 0.80 | GPR35 (0.60) | HPGDSMN1; SMN2TP53TSHRHIF1A | |
| SCHEMBL34473110 | 0.80 | MAPT (0.53) | HPGDSMN1; SMN2TP53TSHRHIF1A | |
| SCHEMBL27721236 | 0.80 | SMN1; SMN2 (0.47) | HPGDSMN1; SMN2TP53TSHRHIF1A | |
| Water SCHEMBL4383863 | 0.78 | GPR35 (0.58) | HPGDSMN1; SMN2TP53TSHRHIF1A | |
| Water SCHEMBL4383860 | 0.78 | GPR35 (0.58) | HPGDSMN1; SMN2TP53TSHRHIF1A | |
| SCHEMBL7063754 | 0.78 | GPR35 (0.55) | HPGDSMN1; SMN2TP53TSHRHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116217566-B | Anti-apoptosis protein BCL-2 inhibitor, pharmaceutical composition and application thereof | 杭州和正医药有限公司 | 2025-05-23 | — | — | CN | disclosed |
| CN-112469713-B | Aryl phosphorus oxide derivative inhibitor, preparation method and application thereof | 江苏豪森药业集团有限公司 | 2023-09-01 | — | — | CN | disclosed |
| CN-116217566-A | Anti-apoptosis protein BCL-2 inhibitor, pharmaceutical composition and application thereof | 杭州和正医药有限公司 | 2023-06-06 | — | — | CN | disclosed |
| CN-116234556-A | Crystal form of aryl phosphorus oxide derivative free alkali and preparation method and application thereof | 江苏豪森药业集团有限公司 | 2023-06-06 | — | — | CN | disclosed |
| CN-114644654-A | Oxidized aryl phosphorus derivative, acid salt or crystal form thereof, and preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2022-06-21 | — | — | CN | disclosed |