SCHEMBL351534

SCHEMBL351534

O=[N+]([O-])c1ccc(O)c(O)c1O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR35 Q9HC97 5/20 0.60
HPGD P15428 3/20 0.55
SMN1; SMN2 Q16637 3/20 0.55
TP53 P04637 2/20 0.55
TSHR P16473 2/20 0.55
HIF1A Q16665 2/20 0.55
CTSB P07858 2/20 0.55
CYP3A4 P08684 1/20 0.55
MAPK1 P28482 3/20 0.52
ALDH1A1 P00352 3/20 0.52
ALOX15 P16050 2/20 0.50
HSD17B10 Q99714 2/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
MAPT P10636 5/20 0.47
CASP6 P55212 2/20 0.47
POLB P06746 1/20 0.47
APEX1 P27695 1/20 0.47
ALDH5A1 P51649 1/20 0.47
ABAT P80404 1/20 0.47
ERN1 O75460 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL4383863 0.98 GPR35 (0.58) GPR35HPGDSMN1; SMN2TP53TSHR
Water SCHEMBL4383860 0.98 GPR35 (0.58) GPR35HPGDSMN1; SMN2TP53TSHR
SCHEMBL3083253 0.90 GPR35 (0.71) GPR35HPGDSMN1; SMN2TP53TSHR
SCHEMBL29533001 0.82 GPR35 (0.59) GPR35HPGDSMN1; SMN2TP53TSHR
SCHEMBL70085 0.82 GPR35 (0.59) GPR35HPGDSMN1; SMN2TP53TSHR
SCHEMBL68675 0.82 GPR35 (0.59) GPR35HPGDSMN1; SMN2TP53TSHR
SCHEMBL12491862 0.80 GPR35 (0.57) GPR35HPGDSMN1; SMN2TP53TSHR
SCHEMBL27718719 0.80 HPGD (0.55) GPR35HPGDSMN1; SMN2TP53TSHR
SCHEMBL27469332 0.80 GPR35 (0.57) GPR35HPGDSMN1; SMN2TP53TSHR
SCHEMBL3280548 0.80 GPR35 (0.54) GPR35HPGDSMN1; SMN2TP53TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 108 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2437791-B1 POTENTIATION OF AUTOIMMUNE AND INFLAMMATORY DISEASE TREATMENTS BY IMMUNE REGULATORY OLIGONUCLEOTIDE (IRO) ANTAGONISTS OF TLR7 AND TLR9 IDERA PHARMACEUTICALS INC (US) 2017-03-22 EP claimed
US-9206430-B2 Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response IDERA PHARMACEUTICALS, INC. (US) 2015-12-08 US claimed
EP-2343307-B1 Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response IDERA PHARMACEUTICALS (US) 2015-08-05 EP claimed
US-8987221-B2 Potentiation of autoimmune and inflammatory disease treatments by immune regulatory oligonucleotide (IRO) antagonists of TLR7 and TLR9 IDERA PHARMACEUTICALS, INC. (US) 2015-03-24 US claimed
US-8853177-B2 Use of inhibitors of toll-like receptors in the prevention and treatment of hypercholesterolemia and hyperlipidemia and diseases related thereto IDERA PHARMACEUTICALS, INC. (US) 2014-10-07 US claimed
US-20130267583-A1 IMMUNE REGULATORY OLIGONUCLEOTIDE (IRO) COMPOUNDS TO MODULATE TOLL-LIKE RECEPTOR BASED IMMUNE RESPONSE IDERA PHARMACEUTICALS, INC. (US) 2013-10-10 US claimed
US-8426375-B2 Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response IDERA PHARMACEUTICALS, INC. (US) 2013-04-23 US claimed
US-8399423-B2 Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response IDERA PHARMACEUTICALS, INC. (US) 2013-03-19 US claimed
US-8383598-B2 Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response IDERA PHARMACEUTICALS, INC. (US) 2013-02-26 US claimed
US-8377898-B2 Antisense oligonucleotides for prevention and/or treatment of infection, asthma, skin, inflammatory and/or autoimmune disorders IDERA PHARMACEUTICALS, INC. (US) 2013-02-19 US claimed
US-8357665-B2 Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response IDERA PHARMACEUTICALS, INC. (US) 2013-01-22 US claimed
EP-2451974-A2 OLIGONUCLEOTIDE-BASED COMPOUNDS AS INHIBITORS OF TOLL-LIKE RECEPTORS Idera Pharmaceuticals, Inc. (US) 2012-05-16 EP claimed
EP-2343307-A1 Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response Idera Pharmaceuticals (US) 2011-07-13 EP claimed
WO-2011005942-A2 OLIGONUCLEOTIDE-BASED COMPOUNDS AS INHIBITORS OF TOLL-LIKE RECEPTORS IDERA PHARMACEUTICALS, INC. (US) 2011-01-13 WO claimed
US-20110009477-A1 OLIGONUCLEOTIDE-BASED COMPOUNDS AS INHIBITORS OF TOLL-LIKE RECEPTORS IDERA PHARMACEUTICALS, INC. (US) 2011-01-13 US claimed
US-7539006-B2 Electrolytic solution for driving electrolytic capacitor and electrolytic capacitor RUBYCON CORPORATION (JP) 2009-05-26 US claimed
US-20070029529-A1 Electrolytic solution for driving electrolytic capacitor and electrolytic capacitor KOMATSU AKIHIKO 2007-02-08 US claimed
US-20040245105-A1 Electrolyte solution for driving electrolytic capacitor and electrolytic capacitor RUBYCON CORPORATION (JP) 2004-12-09 US claimed
EP-1437749-A1 ELECTROLYTE SOLUTION FOR DRIVING ELECTROLYTIC CAPACITOR AND ELECTROLYTIC CAPACITOR Rubycon Corporation (JP) 2004-07-14 EP claimed
EP-4029508-A1 TREATMENT OF CANCER USING TLR9 AGONISTS AND CHECKPOINT INHIBITORS Idera Pharmaceuticals, Inc. (US) 2022-07-20 EP disclosed
EP-3204040-B1 TREATMENT OF CANCER USING TLR9 AGONISTS AND CHECKPOINT INHIBITORS IDERA PHARMACEUTICALS INC (US) 2021-12-08 EP disclosed
EP-2348112-B1 Stabilized immune modulatory RNA (SIMRA) compounds IDERA PHARMACEUTICALS INC (US) 2018-11-28 EP disclosed
US-20180044669-A1 COMPOSITIONS FOR INHIBITING CHECKPOINT GENE EXPRESSION AND USES THEREOF IDERA PHARMACEUTICALS, INC. 2018-02-15 US disclosed
EP-3272870-A1 COMPOSITIONS FOR INHIBITING GENE EXPRESSION AND USES THEREOF Idera Pharmaceuticals, Inc. (US) 2018-01-24 EP disclosed
US-9828601-B2 Compositions for inhibiting checkpoint gene expression and uses thereof IDERA PHARMACEUTICALS, INC. (US) 2017-11-28 US disclosed
EP-2960333-B1 COMPOSITION FOR INHIBITING GENE EXPRESSION AND USES THEREOF IDERA PHARMACEUTICALS INC (US) 2017-10-04 EP disclosed
US-20170274004-A1 TREATMENT OF CANCER USING TLR9 AGONIST WITH CHECKPOINT INHIBITORS IDERA PHARMACEUTICALS INC (US) 2017-09-28 US disclosed
US-20170145412-A1 COMPOSITIONS FOR INHIBITING NLRP3 GENE EXPRESSION AND USES THEREOF IDERA PHARMACEUTICALS, INC. 2017-05-25 US disclosed
EP-2437791-B1 POTENTIATION OF AUTOIMMUNE AND INFLAMMATORY DISEASE TREATMENTS BY IMMUNE REGULATORY OLIGONUCLEOTIDE (IRO) ANTAGONISTS OF TLR7 AND TLR9 IDERA PHARMACEUTICALS INC (US) 2017-03-22 EP disclosed
US-20170009230-A1 COMPOSITIONS FOR INHIBITING DUX4 GENE EXPRESSION AND USES THEREOF IDERA PHARMACEUTICALS, INC. 2017-01-12 US disclosed
US-9453228-B2 Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response IDERA PHARMACEUTICALS, INC. (US) 2016-09-27 US disclosed
US-20160251652-A1 COMPOSITIONS FOR INHIBITING CHECKPOINT GENE EXPRESSION AND USES THEREOF NOVAQUEST CO-INVESTMENT FUND XV, L.P. 2016-09-01 US disclosed
EP-2821488-B1 Novel synthetic agonists of TLR9 IDERA PHARMACEUTICALS INC (US) 2016-07-27 EP disclosed
US-9347064-B2 Methods of treatment using TLR7 and/or TLR9 inhibitors DYNAVAX TECHNOLOGIES CORPORATION (US) 2016-05-24 US disclosed
US-20160138022-A1 IMMUNE REGULATORY OLIGONUCLEOTIDE (IRO) COMPOUNDS TO MODULATE TOLL-LIKE RECEPTOR BASED IMMUNE RESPONSE NOVAQUEST CO-INVESTMENT FUND XV, L.P. 2016-05-19 US disclosed
US-20160101128-A1 TREATMENT OF CANCER USING TLR9 AGONIST WITH CHECKPOINT INHIBITORS IDERA PHARMACEUTICALS, INC. 2016-04-14 US disclosed
US-9243050-B2 Stabilized immune modulatory RNA (SIMRA) compounds for TLR7 and TLR8 Idera Pharamaceuticals, Inc. (US) 2016-01-26 US disclosed
EP-2960333-A1 COMPOSITION FOR INHIBITING GENE EXPRESSION AND USES THEREOF Idera Pharmaceuticals, Inc. (US) 2015-12-30 EP disclosed
EP-2343307-B1 Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response IDERA PHARMACEUTICALS (US) 2015-08-05 EP disclosed
US-20150203850-A1 METHODS OF TREATMENT USING TLR7 AND/OR TLR9 INHIBITORS DYNAVAX TECHNOLOGIES CORPORATION 2015-07-23 US disclosed
EP-1934239-B1 IMMUNE REGULATORY OLIGONUCLEOTIDE (IRO) COMPOUNDS TO MODULATE TOLL-LIKE RECEPTOR BASED IMMUNE RESPONSE IDERA PHARMACEUTICALS INC (US) 2015-07-15 EP disclosed
US-8987221-B2 Potentiation of autoimmune and inflammatory disease treatments by immune regulatory oligonucleotide (IRO) antagonists of TLR7 and TLR9 IDERA PHARMACEUTICALS, INC. (US) 2015-03-24 US disclosed
US-8940310-B2 Methods of treatment using TLR7 and/or TLR9 inhibitors DYNAVAX TECHNOLOGIES CORPORATION (US) 2015-01-27 US disclosed
US-8877722-B2 Compositions for inhibiting gene expression and uses thereof IDERA PHARMACEUTICALS, INC. (US) 2014-11-04 US disclosed
US-20140308300-A1 STABILIZED IMMUNE MODULATORY RNA (SIMRA) COMPOUNDS FOR TLR7 AND TLR8 NOVAQUEST CO-INVESTMENT FUND XV, L.P. 2014-10-16 US disclosed
EP-2726529-A1 HYBRID EPOXY RESINS Dow Global Technologies LLC (US) 2014-05-07 EP disclosed
US-20130142778-A1 COMPOSITIONS FOR INHIBITING GENE EXPRESSION AND USES THEREOF IDERA PHARMACEUTICALS, INC. (US) 2013-06-06 US disclosed
US-8426375-B2 Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response IDERA PHARMACEUTICALS, INC. (US) 2013-04-23 US disclosed
WO-2013055411-A1 HYBRID EPOXY RESINS DOW GLOBAL TECHNOLOGIES LLC (US) 2013-04-18 WO disclosed
US-8399423-B2 Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response IDERA PHARMACEUTICALS, INC. (US) 2013-03-19 US disclosed
US-8362233-B2 Stabilized immune modulatory RNA (SIMRA) compounds IDERA PHARMACEUTICALS, INC. (US) 2013-01-29 US disclosed
US-8357665-B2 Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response IDERA PHARMACEUTICALS, INC. (US) 2013-01-22 US disclosed
US-20120183530-A1 STABILIZED IMMUNE MODULATORY RNA (SIMRA) COMPOUNDS IDERA PHARMACEUTICALS, INC. 2012-07-19 US disclosed
US-8188261-B2 Stabilized immune modulatory RNA (SIMRA) compounds IDERA PHARMACEUTICALS, INC. (US) 2012-05-29 US disclosed
US-8106173-B2 Stabilized immune modulatory RNA (SIMRA) compounds for TLR7 and TLR8 IDERA PHARMACEUTICALS, INC. (US) 2012-01-31 US disclosed
US-20120016004-A1 COMPOSITIONS FOR INHIBITING GENE EXPRESSION AND USES THEREOF IDERA PHARMACEUTICALS, INC. 2012-01-19 US disclosed
EP-2357231-A2 Stabilized immune modulatory RNA (SIMRA) compounds Idera Pharmaceuticals, Inc. (US) 2011-08-17 EP disclosed
EP-2348112-A2 Stabilized immune modulatory RNA (SIMRA) compounds Idera Pharmaceuticals, Inc. (US) 2011-07-27 EP disclosed
US-20110171209-A1 Potentiation of Autoimmune and Inflammatory Disease Treatments by Immune Regulatory Oligonucleotide (IRO) Antagonists of TLR7 and TLR9 IDERA PHARMACEUTICALS, INC. (US) 2011-07-14 US disclosed
US-7960362-B2 Synthetic agonists of TLR9 IDERA PHARMACEUTICALS, INC. (US) 2011-06-14 US disclosed
US-20110009477-A1 OLIGONUCLEOTIDE-BASED COMPOUNDS AS INHIBITORS OF TOLL-LIKE RECEPTORS IDERA PHARMACEUTICALS, INC. (US) 2011-01-13 US disclosed
US-7833331-B2 Non-toxic corrosion-protection pigments based on cobalt UNIVERSITY OF DAYTON (US) 2010-11-16 US disclosed
US-7789958-B2 Non-toxic corrosion-protection pigments based on manganese UNIVERSITY OF DAYTON (US) 2010-09-07 US disclosed
US-20090163628-A1 NON-TOXIC CORROSION-PROTECTION PIGMENTS BASED ON COBALT STURGILL JEFFREY ALLEN 2009-06-25 US disclosed
US-7539006-B2 Electrolytic solution for driving electrolytic capacitor and electrolytic capacitor RUBYCON CORPORATION (JP) 2009-05-26 US disclosed
US-20090098063-A1 IMMUNE REGULATORY OLIGONUCLEOTIDE (IRO) COMPOUNDS TO MODULATE TOLL-LIKE RECEPTOR BASED IMMUNE RESPONSE IDERA PHARMACEUTICALS, INC. 2009-04-16 US disclosed
US-20090087388-A1 IMMUNE REGULATORY OLIGONUCLEOTIDE (IRO) COMPOUNDS TO MODULATE TOLL-LIKE RECEPTOR BASED IMMUNE RESPONSE IDERA PHARMACEUTICALS, INC. 2009-04-02 US disclosed
US-20090060898-A1 Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response IDERA PHARMACEUTICALS, INC. 2009-03-05 US disclosed
US-20090053206-A1 NOVEL SYNTHETIC AGONISTS OF TLR9 IDERA PHARMACEUTICALS, INC. 2009-02-26 US disclosed
US-20090053205-A1 STABILIZED IMMUNE MODULATORY RNA (SIMRA) COMPOUNDS IDERA PHARMACEUTICALS, INC 2009-02-26 US disclosed
US-7422793-B2 Non-toxic corrosion-protection rinses and seals based on rare earth elements UNIVERSITY OF DAYTON (US) 2008-09-09 US disclosed
US-7407711-B2 Non-toxic corrosion-protection conversion coats based on rare earth elements UNIVERSITY OF DAYTON (US) 2008-08-05 US disclosed
US-20080171712-A1 At least two oligonucleotides having modified purine bases, such as deazaguanosines or deaza-adenosines, linked by an alkyl or phenolic diol or triol; vaccines, DNA vaccines; anticarcinogenic, antiallergenic, antiinflammatory agents; bronchodilators IDERA PHARMACEUTICALS, INC. 2008-07-17 US disclosed
US-7294211-B2 Non-toxic corrosion-protection conversion coats based on cobalt UNIVERSITY OF DAYTON (US) 2007-11-13 US disclosed
US-7291217-B2 Non-toxic corrosion-protection pigments based on rare earth elements UNIVERSITY OF DAYTON (US) 2007-11-06 US disclosed
US-20070149673-A1 NON-TOXIC CORROSION-PROTECTION PIGMENTS BASED ON MANGANESE STURGILL JEFFREY A 2007-06-28 US disclosed
US-7235142-B2 Non-toxic corrosion-protection rinses and seals based on cobalt UNIVERSITY OF DAYTON (US) 2007-06-26 US disclosed
CN-1316061-C Composition and treatment liquid for surface treatment, surface treatment method and product with metal material NIPPON BACAREI KAMIYA CORP (JP) 2007-05-16 CN disclosed
US-20070029529-A1 Electrolytic solution for driving electrolytic capacitor and electrolytic capacitor KOMATSU AKIHIKO 2007-02-08 US disclosed
US-20040245105-A1 Electrolyte solution for driving electrolytic capacitor and electrolytic capacitor RUBYCON CORPORATION (JP) 2004-12-09 US disclosed
EP-1472319-A1 NON-TOXIC CORROSION PROTECTION PIGMENTS BASED ON COBALT UNIVERSITY OF DAYTON (US) 2004-11-03 EP disclosed
WO-2004065305-A1 NON-TOXIC CORROSION-PROTECTION PIGMENTS BASED ON MANGANESE UNIVERSITY OF DAYTON (US) 2004-08-05 WO disclosed
EP-1437749-A1 ELECTROLYTE SOLUTION FOR DRIVING ELECTROLYTIC CAPACITOR AND ELECTROLYTIC CAPACITOR Rubycon Corporation (JP) 2004-07-14 EP disclosed
US-20040104377-A1 Non-toxic corrosion-protection pigments based on rare earth elements UNIVERSITY OF DAYTON 2004-06-03 US disclosed
CN-1493712-A Composition and treatment liquid for surface treatment, surface treatment method and product with metal material 日本巴卡黎神谷股份有限公司 2004-05-05 CN disclosed
US-20040020568-A1 Non-toxic corrosion-protection conversion coats based on rare earth elements DAYTON, UNIVERSITY OF 2004-02-05 US disclosed
US-20040016910-A1 Non-toxic corrosion-protection rinses and seals based on rare earth elements DAYTON, UNIVERSITY OF 2004-01-29 US disclosed
US-20040011252-A1 Non-toxic corrosion-protection pigments based on manganese UNIVERSITY OF DAYTON 2004-01-22 US disclosed
US-20030234063-A1 Non-toxic corrosion-protection conversion coats based on cobalt DAYTON, UNIVERSITY OF 2003-12-25 US disclosed
US-20030230363-A1 Non-toxic corrosion-protection rinses and seals based on cobalt UNIVERSITY OF DAYTON 2003-12-18 US disclosed
WO-2003060192-A1 NON-TOXIC CORROSION-PROTECTION RINSES AND SEALS BASED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 WO disclosed
WO-2003060191-A2 NON-TOXIC CORROSION-PROTECTION CONVERSION COATINGES ABSED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 WO disclosed
WO-2003060019-A1 NON-TOXIC CORROSION PROTECTION PIGMENTS BASED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 WO disclosed
EP-0509451-B1 Improved solid electrolytic capacitors and method for manufacturing the same MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) 1995-03-29 EP disclosed
US-5276174-A Alk-1-enyloxy carbonates ISP INVESTMENTS INC. (US) 1994-01-04 US disclosed
EP-0514482-A4 VINYL ETHER COMPOUNDS 1993-04-21 EP disclosed
US-5187650-A Having valve metal with oxide layer, conductive polymer and support electrolyte with nitro group MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1993-02-16 US disclosed
EP-0514482-A1 VINYL ETHER COMPOUNDS ISP INVESTMENTS INC. (US) 1992-11-25 EP disclosed
EP-0509451-A1 Improved solid electrolytic capacitors and method for manufacturing the same MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1992-10-21 EP disclosed
US-5087548-A POSITIVE TYPE RADIATION-SENSITIVE RESIN COMPOSITION JAPAN SYNTHETIC RUBBER CO., INC. (JP) 1992-02-11 US disclosed
WO-1991013052-A1 VINYL ETHER COMPOUNDS ISP INVESTMENTS INC. (US) 1991-09-05 WO disclosed
EP-0227487-A2 Positive type radiation-sensitive resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1987-07-01 EP disclosed
EP-0153642-A2 Process for the preparation of monomeric aromatic hydroxyurethanes BAYER AG (DE) 1985-09-04 EP disclosed
US-4491584-A ANTIARRHYTHMIA AGENTS RIKER LABORATORIES (US) 1985-01-01 US disclosed
EP-0095454-A2 Nuclens-substituted pyrogallol derivatives Gerot-Pharmazeutika Gesellschaft m.b.H. (AT) 1983-11-30 EP disclosed
US-4355141-A NITROGEN-COMPOUND CONTAINING RESOLE RESIN PREVENTS STICKING MITSUI TOATSU CHEMICAL, INC. (JP) 1982-10-19 US disclosed
US-4154941-A ANTIARRHYTHMIC AGENTS RIKER LABORATORIES, INC. (US) 1979-05-15 US disclosed
US-4071524-A Derivatives of urea RIKER LABORATORIES, INC. (US) 1978-01-31 US disclosed
US-4071524-A Derivatives of urea RIKER LABORATORIES, INC. (US) 1978-01-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (19 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090053206-A1 NOVEL SYNTHETIC AGONISTS OF TLR9 TLR9, TLR3, TLR7 GPR35 108/4885HPGD 3125/4885SMN1; SMN2 4242/4885
US-20170145412-A1 COMPOSITIONS FOR INHIBITING NLRP3 GENE EXPRESSION AND USES THEREOF NLRP3, RNMT, NOD1 GPR35 1822/4885HPGD 3411/4885SMN1; SMN2 3008/4885
US-20160101128-A1 TREATMENT OF CANCER USING TLR9 AGONIST WITH CHECKPOINT INHIBITORS TLR9, TLR3, TLR7 GPR35 211/4885HPGD 4283/4885SMN1; SMN2 2898/4885
US-20110009477-A1 OLIGONUCLEOTIDE-BASED COMPOUNDS AS INHIBITORS OF TOLL-LIKE RECEPTORS TLR3, TLR9, TLR1 GPR35 213/4885HPGD 4498/4885SMN1; SMN2 3841/4885
US-20160138022-A1 IMMUNE REGULATORY OLIGONUCLEOTIDE (IRO) COMPOUNDS TO MODULATE TOLL-LIKE RECEPTOR BASED IMMUNE RESPONSE TLR3, TLR9, TLR5 GPR35 87/4885HPGD 4418/4885SMN1; SMN2 4083/4885
US-20180044669-A1 COMPOSITIONS FOR INHIBITING CHECKPOINT GENE EXPRESSION AND USES THEREOF CD274, PDCD1LG2, PDCD1 GPR35 1624/4885HPGD 4222/4885SMN1; SMN2 1735/4885
US-20120016004-A1 COMPOSITIONS FOR INHIBITING GENE EXPRESSION AND USES THEREOF RNGTT, NSUN2, RTCB GPR35 4267/4885HPGD 4586/4885SMN1; SMN2 951/4885
US-20170009230-A1 COMPOSITIONS FOR INHIBITING DUX4 GENE EXPRESSION AND USES THEREOF DDX21, DDX24, DDX3X GPR35 4327/4885HPGD 3578/4885SMN1; SMN2 1177/4885
US-20160251652-A1 COMPOSITIONS FOR INHIBITING CHECKPOINT GENE EXPRESSION AND USES THEREOF CD274, PDCD1LG2, PDCD1 GPR35 1624/4885HPGD 4222/4885SMN1; SMN2 1735/4885
US-20110171209-A1 Potentiation of Autoimmune and Inflammatory Disease Treatments by Immune Regulatory Oligonucleotide (IRO) Antagonists of TLR7 and TLR9 TLR9, TLR7, TLR3 GPR35 284/4885HPGD 4489/4885SMN1; SMN2 2459/4885
US-20090087388-A1 IMMUNE REGULATORY OLIGONUCLEOTIDE (IRO) COMPOUNDS TO MODULATE TOLL-LIKE RECEPTOR BASED IMMUNE RESPONSE TLR3, TLR9, TLR5 GPR35 87/4885HPGD 4418/4885SMN1; SMN2 4083/4885
US-20130142778-A1 COMPOSITIONS FOR INHIBITING GENE EXPRESSION AND USES THEREOF AGO2, NSUN2, ZFR GPR35 4740/4885HPGD 4731/4885SMN1; SMN2 1291/4885
US-20090060898-A1 Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response TLR3, TLR9, TLR5 GPR35 87/4885HPGD 4418/4885SMN1; SMN2 4083/4885
US-20080171712-A1 At least two oligonucleotides having modified purine bases, such as deazaguanosines or deaza-adenosines, linked by an alkyl or phenolic diol or triol; vaccines, DNA vaccines; anticarcinogenic, antiallergenic, antiinflammatory agents; bronchodilators TLR8, TLR7, TLR9 GPR35 167/4885HPGD 3729/4885SMN1; SMN2 2543/4885
US-20090098063-A1 IMMUNE REGULATORY OLIGONUCLEOTIDE (IRO) COMPOUNDS TO MODULATE TOLL-LIKE RECEPTOR BASED IMMUNE RESPONSE TLR3, TLR9, TLR1 GPR35 338/4885HPGD 4517/4885SMN1; SMN2 3163/4885
US-20170274004-A1 TREATMENT OF CANCER USING TLR9 AGONIST WITH CHECKPOINT INHIBITORS TLR9, TLR3, TLR7 GPR35 211/4885HPGD 4283/4885SMN1; SMN2 2898/4885
US-20120183530-A1 STABILIZED IMMUNE MODULATORY RNA (SIMRA) COMPOUNDS TLR8, TLR7, TLR9 GPR35 2380/4885HPGD 4838/4885SMN1; SMN2 311/4885
US-20140308300-A1 STABILIZED IMMUNE MODULATORY RNA (SIMRA) COMPOUNDS FOR TLR7 AND TLR8 TLR8, TLR7, TLR9 GPR35 1993/4885HPGD 4809/4885SMN1; SMN2 400/4885
US-20090053205-A1 STABILIZED IMMUNE MODULATORY RNA (SIMRA) COMPOUNDS TLR8, TLR7, TLR9 GPR35 2380/4885HPGD 4838/4885SMN1; SMN2 311/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.