Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 7/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 7/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.49 |
| ▸ | HTR1A | P08908 | 8/20 | 0.49 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23213411 | 1.00 | CHRM4 (0.50) | CHRM4CHRM1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL23213409 | 1.00 | CHRM4 (0.50) | CHRM4CHRM1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL23230076 | 0.91 | HTR1A (0.53) | CHRM4CHRM1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL23213301 | 0.89 | CHRM4 (0.47) | CHRM4CHRM1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL26781057 | 0.88 | CHRM4 (0.56) | CHRM4CHRM1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL23213607 | 0.87 | CHRM4 (0.54) | CHRM4CHRM1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL23213495 | 0.87 | CHRM4 (0.63) | CHRM4CHRM1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL23213492 | 0.87 | CHRM4 (0.63) | CHRM4CHRM1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL23229980 | 0.86 | KDM1A (0.45) | CHRM4CHRM1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL23213686 | 0.84 | CHRM4 (0.55) | CHRM4CHRM1SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119390705-A | 5-Oxa-2-azaspiro [3.4] octane derivatives as M4 agonists | 诺华股份有限公司 | 2025-02-07 | — | — | CN | disclosed |
| CN-114555606-B | 5-Oxa-2-azaspiro [3.4] octane derivatives as M4 agonists | 诺华股份有限公司 | 2024-10-01 | — | — | CN | disclosed |
| CN-114555606-A | 5-oxa-2-azaspiro [3.4] octane derivatives as M4 agonists | 诺华股份有限公司 | 2022-05-27 | — | — | CN | disclosed |