SCHEMBL12735554

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL19160156	0.83	VNN1 (0.40)	POLBVNN1KMT2APKMSMN1; SMN2
	SCHEMBL13010322	0.82	SMN1; SMN2 (0.47)	VNN1KMT2ASMN1; SMN2ALDH1A1CYP1A2
	SCHEMBL368420	0.78	VNN1 (0.40)	VNN1KMT2AALDH1A1NAMPTFPR1
	SCHEMBL29542823	0.78	POLB (0.44)	POLBKMT2ANAMPTCYP1A2
	SCHEMBL2428734	0.77	VNN1 (0.40)	VNN1ALDH1A1NAMPTFPR1FPR2
	SCHEMBL13010536	0.77	VNN1 (0.40)	VNN1ALDH1A1NAMPTFPR1FPR2
	SCHEMBL27012796	0.76	OPRM1 (0.39)	VNN1KMT2ASMN1; SMN2ALDH1A1EPHX2
	SCHEMBL27009205	0.76	EPHX2 (0.45)	VNN1KMT2ASMN1; SMN2ALDH1A1EPHX2
	SCHEMBL23486716	0.75	NPC1 (0.61)	KMT2ASMN1; SMN2ALDH1A1NAMPTEPHX2
	SCHEMBL29985164	0.73	POLB (0.47)	POLBKMT2AALDH1A1CYP1A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.