SCHEMBL296199

SCHEMBL296199

CCO[CH]COCCOCCO

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.48
MEN1 O00255 3/20 0.48
KMT2A Q03164 3/20 0.48
TSHR P16473 2/20 0.43
MAPK1 P28482 2/20 0.43
THRB P10828 1/20 0.43
HTT P42858 1/20 0.43
MAPT P10636 1/20 0.43
APP P05067 2/20 0.30
USP2 O75604 1/20 0.30
LMNA P02545 1/20 0.30
CYP3A4 P08684 1/20 0.30
CASP1 P29466 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
SLCO1B3 Q9NPD5 1/20 0.30
SLCO1B1 Q9Y6L6 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9550981 0.96
SCHEMBL363155 0.84 ALDH1A1 (0.36) ALDH1A1TSHRTHRB
SCHEMBL4216111 0.81 ALDH1A1 (0.38) ALDH1A1TSHRTHRB
SCHEMBL6434546 0.79 TSHR (0.47) ALDH1A1MEN1KMT2ATSHRMAPK1
SCHEMBL277199 0.77
Tetraethylene Glycol SCHEMBL15376842 0.76 MEN1 (0.50) ALDH1A1MEN1KMT2ATSHRMAPK1
Pentaethylene Glycol SCHEMBL16108320 0.76 ALDH1A1 (0.50) ALDH1A1MEN1KMT2ATSHRMAPK1
Triethylene Glycol SCHEMBL15375859 0.76 MEN1 (0.50) ALDH1A1MEN1KMT2ATSHRMAPK1
Triethylene Glycol SCHEMBL1129902 0.76 ALDH1A1 (0.50) ALDH1A1MEN1KMT2ATSHRMAPK1
SCHEMBL4956991 0.74 TSHR (0.38) ALDH1A1MEN1KMT2ATSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9044452-B2 Use of resiniferatoxin (RTX) for producing an agent for treating joint pains and method for applying said agent MESTEX AG (CH) 2015-06-02 US claimed
EP-1838301-B1 USE OF RESINIFERATOXIN (RTX) FOR THE PREPARATION OF AN AGENT FOR THE TREATMENT OF PAIN MESTEX AG (CH) 2015-01-28 EP claimed
EP-1830835-B1 USE OF A VANILLOID RECEPTOR AGONIST TOGETHER WITH A GLYCOSAMINOGLYCAN OR PROTEOGLYCAN FOR PRODUCING AN AGENT FOR TREATING ARTICULAR PAINS AND METHOD FOR APPLYING SAID AGENT MESTEX AG (CH) 2012-03-14 EP claimed
US-20100196281-A1 USE OF RESINIFERATOXIN (RTX) FOR PRODUCING AN AGENT FOR TREATING JOINT PAINS AND METHOD FOR APPLYING SAID AGENT MESTEX AG (CH) 2010-08-05 US claimed
US-20080153780-A1 Use Of A Vanilloid Receptor Agonist Together With A Glycosaminoglycan Or Proteoglycan For Producing An Agent For Treating Articular Pains And Method For Applying Said Agent MESTEX AG (CH) 2008-06-26 US claimed
US-20080139641-A1 Use Of Resiniferatoxin (Rtx) For Producing An Agent For Treating Joint Pains And Method For Applying Said Agent MESTEX AG (CH) 2008-06-12 US claimed
EP-3976081-A1 HLA TUMOR ANTIGEN PEPTIDES OF CLASS I AND II FOR TREATING MAMMARY/BREAST CARCINOMAS PMCR GMBH (DE) 2022-04-06 EP disclosed
EP-3946317-A1 COMPOSITION COMPRISING CAPSAICIN OR A CAPSACINOID FOR POSTOPERATIVE PAIN CONTROL Mestex AG (CH) 2022-02-09 EP disclosed
US-20220008384-A1 COMPOSITION COMPRISING CAPSAICIN OR A CAPSACINOID FOR POSTOPERATIVE PAIN CONTROL MESTEX AG (CH) 2022-01-13 US disclosed
WO-2020245126-A1 HLA TUMOR ANTIGEN PEPTIDES OF CLASS I AND II FOR TREATING MAMMARY/BREAST CARCINOMAS PMCR GmbH (DE) 2020-12-10 WO disclosed
WO-2020191506-A1 COMPOSITION COMPRISING CAPSAICIN OR A CAPSACINOID FOR POSTOPERATIVE PAIN CONTROL MESTEX AG (CH) 2020-10-01 WO disclosed
US-9044452-B2 Use of resiniferatoxin (RTX) for producing an agent for treating joint pains and method for applying said agent MESTEX AG (CH) 2015-06-02 US disclosed
US-8703741-B2 Method of treating articular pain using a vanilloid receptor agonist together with a glycosaminoglycan or proteoglycan MESTEX AG (CH) 2014-04-22 US disclosed
US-20100196281-A1 USE OF RESINIFERATOXIN (RTX) FOR PRODUCING AN AGENT FOR TREATING JOINT PAINS AND METHOD FOR APPLYING SAID AGENT MESTEX AG (CH) 2010-08-05 US disclosed
US-20100047181-A1 MIXTURE OF A VANILLOID RECEPTOR AGONIST AND A SUBSTANCE INHIBITING NERVE REGENERATION, USE THEREOF FOR PRODUCING A PAINKILLER, AND METHOD FOR APPLYING SAID PAINKILLER MESTEX AG (CH) 2010-02-25 US disclosed
US-20080153780-A1 Use Of A Vanilloid Receptor Agonist Together With A Glycosaminoglycan Or Proteoglycan For Producing An Agent For Treating Articular Pains And Method For Applying Said Agent MESTEX AG (CH) 2008-06-26 US disclosed
US-20080139641-A1 Use Of Resiniferatoxin (Rtx) For Producing An Agent For Treating Joint Pains And Method For Applying Said Agent MESTEX AG (CH) 2008-06-12 US disclosed