SCHEMBL6434546

SCHEMBL6434546

OCCO[CH]COCCO

nearest known ligand 0.47

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.47
MAPK1 P28482 1/20 0.47
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
ALDH1A1 P00352 1/20 0.39
THRB P10828 1/20 0.31
HTT P42858 1/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4956991 0.84 TSHR (0.38) TSHRMAPK1MEN1KMT2AALDH1A1
SCHEMBL9550981 0.82
SCHEMBL6435525 0.79 TSHR (0.32) TSHRMAPK1
SCHEMBL296199 0.79 ALDH1A1 (0.48) TSHRMAPK1MEN1KMT2AALDH1A1
SCHEMBL14188815 0.74 TSHR (0.43) TSHRMAPK1MEN1KMT2AALDH1A1
SCHEMBL10584945 0.73 TSHR (0.56) TSHRMAPK1MEN1KMT2AALDH1A1
SCHEMBL6435011 0.73
SCHEMBL11489752 0.73 TSHR (0.56) TSHRMAPK1MEN1KMT2AALDH1A1
SCHEMBL11489750 0.73 TSHR (0.56) TSHRMAPK1MEN1KMT2AALDH1A1
SCHEMBL15796470 0.71 TSHR (0.53) TSHRMAPK1MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1172400-B1 THERMOPLASTIC RESIN FILM WITH SATISFACTORY PRINTABILITY YUPO CORP (JP) 2005-12-28 EP disclosed
US-6586106-B2 Ink transfer, adhesion and aging stability, and being satisfactory in back ghost when offset printing using oxidation polymerization type ink is performed on both faces YUPO CORPORATION (JP) 2003-07-01 US disclosed
US-20020054991-A1 Thermoplastic resin film satisfactory in printability YUPO CORPORATION (JP) 2002-05-09 US disclosed
EP-1172400-A1 THERMOPLASTIC RESIN FILM WITH SATISFACTORY PRINTABILITY Yupo Corporation (JP) 2002-01-16 EP disclosed