SCHEMBL29619912

SCHEMBL29619912

N#Cc1ccnc2ccccc12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NCF1 P14598 1/20 0.50
KDM4E B2RXH2 4/20 0.47
ALDH1A1 P00352 4/20 0.47
MAPT P10636 4/20 0.47
MEN1 O00255 3/20 0.47
HPGD P15428 3/20 0.47
KMT2A Q03164 3/20 0.47
ALOX15 P16050 2/20 0.47
HSD17B10 Q99714 2/20 0.47
TP53 P04637 1/20 0.47
TSHR P16473 1/20 0.47
CASP1 P29466 1/20 0.47
BRCA1 P38398 1/20 0.47
LOXL2 Q9Y4K0 1/20 0.47
LRRK2 Q5S007 2/20 0.46
TGFBR1 P36897 1/20 0.46
HTR1A P08908 2/20 0.44
ADRA1D P25100 2/20 0.44
ADRA1A P35348 2/20 0.44
ADRA1B P35368 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL828123 1.00 NCF1 (0.50) NCF1KDM4EALDH1A1MAPTMEN1
Iodomethane SCHEMBL11423859 0.94 LRRK2 (0.46) NCF1KDM4EALDH1A1MAPTMEN1
Quinoline SCHEMBL28074108 0.89 ALDH1A1 (0.57) NCF1KDM4EALDH1A1MAPTMEN1
SCHEMBL566054 0.86 MAPT (0.52) KDM4EALDH1A1MAPTMEN1HPGD
SCHEMBL15947627 0.83 NCF1 (0.54) NCF1KDM4EALDH1A1MAPTMEN1
Quinoline SCHEMBL28251318 0.82 ALDH1A1 (0.57) KDM4EALDH1A1MAPTMEN1HPGD
SCHEMBL29077121 0.80 ALDH1A1 (0.47) NCF1KDM4EALDH1A1MAPTMEN1
SCHEMBL736202 0.79 NCF1 (0.50) NCF1KDM4EALDH1A1MAPTMEN1
SCHEMBL21858489 0.79 NCF1 (0.50) NCF1KDM4EALDH1A1MAPTMEN1
SCHEMBL3090736 0.79 NCF1 (0.50) NCF1KDM4EALDH1A1MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120028308-A Small molecule Raman probe, bar code probe, encoding method and application thereof 北京大学 2025-05-23 CN disclosed
WO-2024026423-A1 SUBSTITUTED QUINOLINE DERIVATIVES AS PI3K INHIBITORS BLACK DIAMOND THERAPEUTICS, INC. (US) 2024-02-01 WO disclosed
WO-2022083731-A1 FUSED RING-CONTAINING COMPOUND, APPLICATION THEREOF, AND COMPOSITION CONTAINING SAME 健艾仕生物医药有限公司 2022-04-28 WO disclosed