Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 7/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3184431 | 1.00 | LMNA (0.55) | LMNANPSR1TSHRUSP2MAPK1 | |
| SCHEMBL28439543 | 0.79 | LMNA (0.41) | LMNANPSR1TSHRUSP2MAPK1 | |
| SCHEMBL28439544 | 0.77 | LMNA (0.40) | LMNANPSR1TSHRUSP2MAPK1 | |
| SCHEMBL2393621 | 0.74 | LMNA (0.57) | LMNANPSR1TSHRUSP2MAPK1 | |
| SCHEMBL26364047 | 0.73 | LMNA (0.56) | LMNANPSR1TSHRUSP2MAPK1 | |
| SCHEMBL2956570 | 0.73 | LMNA (0.56) | LMNANPSR1TSHRUSP2MAPK1 | |
| SCHEMBL28226781 | 0.73 | LMNA (0.56) | LMNANPSR1TSHRUSP2MAPK1 | |
| SCHEMBL7879104 | 0.71 | LMNA (0.54) | LMNANPSR1TSHRUSP2MAPK1 | |
| SCHEMBL29522421 | 0.71 | LMNA (1.00) | LMNANPSR1TSHRUSP2MAPK1 | |
| SCHEMBL23198959 | 0.70 | LMNA (0.53) | LMNANPSR1TSHRUSP2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111548291-B | Environment-friendly synthetic method of scorch retarder N-phenyl-N-trichloromethylthio benzenesulfonamide | 山东阳谷华泰化工股份有限公司 | 2022-06-21 | — | — | CN | disclosed |