Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2393621 | 0.78 | LMNA (0.57) | LMNANPSR1TSHRUSP2MAPK1 | |
| SCHEMBL28226781 | 0.77 | LMNA (0.56) | LMNANPSR1TSHRUSP2MAPK1 | |
| SCHEMBL26364047 | 0.77 | LMNA (0.56) | LMNANPSR1TSHRUSP2MAPK1 | |
| SCHEMBL7879104 | 0.76 | LMNA (0.54) | LMNANPSR1TSHRUSP2MAPK1 | |
| SCHEMBL23198959 | 0.74 | LMNA (0.53) | LMNANPSR1TSHRUSP2MAPK1 | |
| SCHEMBL22129838 | 0.74 | LMNA (0.53) | LMNANPSR1TSHRUSP2MAPK1 | |
| SCHEMBL9166728 | 0.74 | LMNA (0.53) | LMNANPSR1TSHRUSP2MAPK1 | |
| SCHEMBL29367208 | 0.74 | LMNA (0.53) | LMNANPSR1TSHRUSP2MAPK1 | |
| SCHEMBL29638140 | 0.74 | LMNA (0.53) | LMNANPSR1TSHRUSP2MAPK1 | |
| SCHEMBL29620404 | 0.73 | LMNA (0.55) | LMNANPSR1TSHRUSP2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170130161-A1 | COMPRESSOR OIL WITH BIOBASED BASE OIL | NOVVI LLC | 2017-05-11 | — | — | US | disclosed |
| EP-2231422-A1 | RUN-FLAT TIRE | Pirelli Tyre S.P.A. (IT) | 2010-09-29 | — | — | EP | disclosed |
| WO-2009080144-A1 | RUN-FLAT TIRE | PIRELLI TYRE S.P.A. (IT) | 2009-07-02 | — | — | WO | disclosed |