Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 3/20 | 0.40 |
| ▸ | KDM1A | O60341 | 3/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.39 |
| ▸ | PDE2A | O00408 | 3/20 | 0.37 |
| ▸ | AKT1 | P31749 | 3/20 | 0.35 |
| ▸ | RPS6KA1 | Q15418 | 3/20 | 0.35 |
| ▸ | PRKCA | P17252 | 1/20 | 0.35 |
| ▸ | GRK2 | P25098 | 1/20 | 0.35 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16043564 | 1.00 | ADRB2 (0.40) | ADRB2KDM1AKCNH2KDM1BPDE2A | |
| SCHEMBL31590279 | 1.00 | ADRB2 (0.40) | ADRB2KDM1AKCNH2KDM1BPDE2A | |
| SCHEMBL15023130 | 1.00 | ADRB2 (0.40) | ADRB2KDM1AKCNH2KDM1BPDE2A | |
| SCHEMBL27357109 | 1.00 | ADRB2 (0.40) | ADRB2KDM1AKCNH2KDM1BPDE2A | |
| SCHEMBL7563537 | 0.83 | ADRB2 (0.45) | ADRB2PDE2AAKT1RPS6KA1PRKCA | |
| SCHEMBL2609188 | 0.83 | LMNA (0.40) | ADRB2KDM1AKCNH2KDM1BRCOR1 | |
| SCHEMBL21831869 | 0.81 | KDM1A (0.36) | ADRB2KDM1AKCNH2KDM1BRCOR1 | |
| SCHEMBL30910946 | 0.81 | KDM1A (0.36) | ADRB2KDM1AKCNH2KDM1BRCOR1 | |
| SCHEMBL1585297 | 0.80 | ADRB2 (0.50) | ADRB2PDE2AAKT1RPS6KA1PRKCA | |
| SCHEMBL6814502 | 0.80 | ADRB2 (0.44) | ADRB2PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114555597-B | Isocitrate Dehydrogenase (IDH) inhibitors | 浙江迈同生物医药有限公司 | 2024-06-04 | — | — | CN | disclosed |
| EP-4041732-A1 | ISO-CITRATE DEHYDROGENASE (IDH) INHIBITOR | ZHEJIANG METON PHARMACEUTICAL CO., LTD (CN) | 2022-08-17 | — | — | EP | disclosed |
| CN-114555597-A | Isocitrate Dehydrogenase (IDH) inhibitors | 浙江迈同生物医药有限公司 | 2022-05-27 | — | — | CN | disclosed |