Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.37 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.36 |
| ▸ | LOX | P28300 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 2/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | NT5E | P21589 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20875536 | 1.00 | KDM4E (0.39) | KDM4EALDH1A1SMN1; SMN2LOXL2RAD51 | |
| SCHEMBL18113431 | 0.89 | KDM4E (0.38) | KDM4EALDH1A1SMN1; SMN2LOXL2RAD51 | |
| SCHEMBL15801545 | 0.86 | KDM4E (0.36) | KDM4EALDH1A1SMN1; SMN2LOXL2RAD51 | |
| SCHEMBL484767 | 0.84 | LOXL2 (0.52) | KDM4EALDH1A1SMN1; SMN2LOXL2RAD51 | |
| SCHEMBL29426991 | 0.84 | SMN1; SMN2 (0.41) | KDM4EALDH1A1SMN1; SMN2SYKPTGS1 | |
| SCHEMBL29581126 | 0.84 | LOXL2 (0.52) | KDM4EALDH1A1SMN1; SMN2LOXL2RAD51 | |
| SCHEMBL571943 | 0.84 | SMN1; SMN2 (0.41) | KDM4EALDH1A1SMN1; SMN2SYKPTGS1 | |
| SCHEMBL28406030 | 0.83 | SMN1; SMN2 (0.38) | KDM4EALDH1A1SMN1; SMN2LOXL2RAD51 | |
| SCHEMBL28400269 | 0.83 | HSD11B1 (0.40) | KDM4EALDH1A1SMN1; SMN2LOXL2RAD51 | |
| Bromide SCHEMBL15720464 | 0.83 | LOXL2 (0.50) | KDM4EALDH1A1SMN1; SMN2LOXL2RAD51 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4554938-A1 | TYROSINE KINASE 2 INHIBITORS AND USES THEREOF | Biogen MA Inc. (US) | 2025-05-21 | — | — | EP | disclosed |
| CN-119894879-A | Tyrosine kinase 2 inhibitors and uses thereof | 渤健马萨诸塞州股份有限公司 | 2025-04-25 | — | — | CN | disclosed |
| CN-114555597-B | Isocitrate Dehydrogenase (IDH) inhibitors | 浙江迈同生物医药有限公司 | 2024-06-04 | — | — | CN | disclosed |
| WO-2024015497-A1 | TYROSINE KINASE 2 INHIBITORS AND USES THEREOF | BIOGEN MA INC. (US) | 2024-01-18 | — | — | WO | disclosed |
| EP-4041732-A1 | ISO-CITRATE DEHYDROGENASE (IDH) INHIBITOR | ZHEJIANG METON PHARMACEUTICAL CO., LTD (CN) | 2022-08-17 | — | — | EP | disclosed |
| CN-114555597-A | Isocitrate Dehydrogenase (IDH) inhibitors | 浙江迈同生物医药有限公司 | 2022-05-27 | — | — | CN | disclosed |