SCHEMBL2962079

SCHEMBL2962079

CC1=CCc2cc(-c3ccccc3C)cc(Br)c21

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIA1 P42261 1/20 0.38
CACNG8 Q8WXS5 1/20 0.38
ADORA1 P30542 1/20 0.35
CA12 O43570 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA9 Q16790 1/20 0.34
ALDH1A1 P00352 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
MEN1 O00255 1/20 0.33
MAPT P10636 1/20 0.33
KMT2A Q03164 1/20 0.33
CD274 Q9NZQ7 1/20 0.32
HTR7 P34969 3/20 0.32
HTR1A P08908 1/20 0.32
CREBBP Q92793 2/20 0.32
MCL1 Q07820 1/20 0.31
NPC1 O15118 1/20 0.31
TSHR P16473 1/20 0.31
RAB9A P51151 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2961516 0.88 CD274 (0.33) ALDH1A1SMN1; SMN2MEN1MAPTKMT2A
SCHEMBL2973870 0.83 CNR1 (0.38) CA12CA1CA2CA9ALDH1A1
SCHEMBL2962460 0.83 CRHBP (0.43) ALDH1A1SMN1; SMN2MEN1MAPTKMT2A
SCHEMBL2973964 0.79 PPARA (0.31)
SCHEMBL2975178 0.77 CA12 (0.35) GRIA1CACNG8CA12CA1CA2
SCHEMBL2962077 0.76 ALDH1A1 (0.44) ALDH1A1SMN1; SMN2MEN1MAPTKMT2A
SCHEMBL2958716 0.76 MEN1 (0.48) ALDH1A1SMN1; SMN2MEN1MAPTKMT2A
SCHEMBL2962738 0.72 ADORA1 (0.32) ADORA1ALDH1A1SMN1; SMN2CD274HTR7
SCHEMBL2974247 0.72 ALDH1A1 (0.35) GRIA1CACNG8ALDH1A1SMN1; SMN2CD274
SCHEMBL2969468 0.72 ALDH1A1 (0.35) GRIA1CACNG8ALDH1A1SMN1; SMN2CD274

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7763562-B2 Heteroatom bridged metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2010-07-27 US disclosed
US-20070135597-A1 Heteroatom bridged metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. 2007-06-14 US disclosed
WO-2006065809-A2 HETEROATOM BRIDGED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2006-06-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070135597-A1 Heteroatom bridged metallocene compounds for olefin polymerization AP2M1, AP1M1, PYM1 GRIA1 1624/4885CACNG8 1327/4885ADORA1 2858/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.