Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 9/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 2/20 | 0.38 |
| ▸ | FLT1 | P17948 | 1/20 | 0.38 |
| ▸ | FLT4 | P35916 | 1/20 | 0.38 |
| ▸ | VCP | P55072 | 1/20 | 0.37 |
| ▸ | VNN1 | O95497 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22925657 | 1.00 | TRPV1 (0.42) | TRPV1FAAHNPC1RAB9ADGAT1 | |
| SCHEMBL29621000 | 0.87 | VCP (0.44) | TRPV1FAAHNPC1RAB9ADGAT1 | |
| SCHEMBL28733674 | 0.87 | VCP (0.44) | TRPV1FAAHNPC1RAB9ADGAT1 | |
| SCHEMBL29621154 | 0.83 | HSD11B1 (0.46) | FAAHNPC1RAB9AVCPVNN1 | |
| SCHEMBL22925866 | 0.83 | HSD11B1 (0.46) | FAAHNPC1RAB9AVCPVNN1 | |
| SCHEMBL22925570 | 0.83 | TRPV1 (0.46) | TRPV1NPC1RAB9ADGAT1KDR | |
| SCHEMBL22925659 | 0.82 | TRPV1 (0.45) | TRPV1DGAT1KDRHDAC1HDAC6 | |
| SCHEMBL29696299 | 0.82 | TRPV1 (0.45) | TRPV1DGAT1KDRHDAC1HDAC6 | |
| SCHEMBL22925658 | 0.82 | TRPV1 (0.47) | TRPV1DGAT1KDRFLT1FLT4 | |
| SCHEMBL22925662 | 0.79 | TRPV1 (0.45) | TRPV1DGAT1KDRFLT1FLT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114450281-B | Inhibitor compounds | 辛塞拉治疗私人有限公司 | 2024-08-16 | — | — | CN | disclosed |
| EP-4003986-A1 | INHIBITOR COMPOUNDS | Cincera Therapeutics Pty Ltd (AU) | 2022-06-01 | — | — | EP | disclosed |
| CN-114450281-A | Inhibitor compounds | 辛塞拉治疗私人有限公司 | 2022-05-06 | — | — | CN | disclosed |