Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 10/20 | 0.62 |
| ▸ | FLT1 | P17948 | 4/20 | 0.44 |
| ▸ | KDR | P35968 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | QPCT | Q16769 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28733794 | 1.00 | GSK3B (0.62) | GSK3BFLT1KDRNPC1ACHE | |
| SCHEMBL24636885 | 0.86 | NPSR1 (0.47) | GSK3BFLT1KDRNPC1CHEK1 | |
| SCHEMBL29621039 | 0.86 | NPSR1 (0.47) | GSK3BFLT1KDRNPC1CHEK1 | |
| SCHEMBL29620967 | 0.83 | TRPV1 (0.47) | GSK3BFLT1KDRCHEK1 | |
| SCHEMBL22925496 | 0.83 | TRPV1 (0.47) | GSK3BFLT1KDRCHEK1 | |
| SCHEMBL28733654 | 0.83 | QPCT (0.43) | GSK3BACHECHEK1QPCT | |
| SCHEMBL29620959 | 0.83 | QPCT (0.43) | GSK3BACHECHEK1QPCT | |
| SCHEMBL22925913 | 0.79 | HDAC6 (0.43) | CHEK1 | |
| SCHEMBL24636908 | 0.79 | HSD11B1 (0.45) | GSK3BCHEK1 | |
| SCHEMBL29620964 | 0.79 | HSD11B1 (0.45) | GSK3BCHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114450281-B | Inhibitor compounds | 辛塞拉治疗私人有限公司 | 2024-08-16 | — | — | CN | disclosed |
| EP-4003986-A1 | INHIBITOR COMPOUNDS | Cincera Therapeutics Pty Ltd (AU) | 2022-06-01 | — | — | EP | disclosed |
| CN-114450281-A | Inhibitor compounds | 辛塞拉治疗私人有限公司 | 2022-05-06 | — | — | CN | disclosed |