Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.45 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 17/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24636908 | 1.00 | HSD11B1 (0.45) | HSD11B1DGAT1CHEK1GSK3B | |
| SCHEMBL22925913 | 0.80 | HDAC6 (0.43) | DGAT1CHEK1 | |
| SCHEMBL29620971 | 0.79 | GSK3B (0.62) | CHEK1GSK3B | |
| SCHEMBL22925496 | 0.79 | TRPV1 (0.47) | CHEK1GSK3B | |
| SCHEMBL28733794 | 0.79 | GSK3B (0.62) | CHEK1GSK3B | |
| SCHEMBL29620967 | 0.79 | TRPV1 (0.47) | CHEK1GSK3B | |
| SCHEMBL22925878 | 0.79 | HSD11B1 (0.49) | HSD11B1 | |
| SCHEMBL22925622 | 0.77 | DGAT1 (0.41) | DGAT1CHEK1 | |
| SCHEMBL31013378 | 0.77 | HSD11B1 (0.45) | HSD11B1GSK3B | |
| SCHEMBL22925671 | 0.77 | HSD11B1 (0.45) | HSD11B1GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114450281-B | Inhibitor compounds | 辛塞拉治疗私人有限公司 | 2024-08-16 | — | — | CN | disclosed |
| EP-4003986-A1 | INHIBITOR COMPOUNDS | Cincera Therapeutics Pty Ltd (AU) | 2022-06-01 | — | — | EP | disclosed |
| CN-114450281-A | Inhibitor compounds | 辛塞拉治疗私人有限公司 | 2022-05-06 | — | — | CN | disclosed |