Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 7/20 | 0.48 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CCR6 | P51684 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29076741 | 1.00 | PGR (0.48) | PGRADAMTS5BCHEALDH1A1MITF | |
| SCHEMBL29621965 | 0.95 | PGR (0.52) | PGRADAMTS5BCHEALDH1A1CYP3A4 | |
| SCHEMBL29621911 | 0.95 | PGR (0.55) | PGRALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL29076750 | 0.95 | PGR (0.52) | PGRADAMTS5BCHEALDH1A1CYP3A4 | |
| SCHEMBL29076770 | 0.86 | PGR (0.48) | PGRADAMTS5ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL29621959 | 0.86 | PGR (0.48) | PGRADAMTS5ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL29621937 | 0.83 | PGR (0.40) | PGRCYP3A4CYP2C19PDE4APDE4B | |
| SCHEMBL29621927 | 0.83 | PGR (0.40) | PGRCYP3A4CYP2C19PDE4APDE4B | |
| SCHEMBL29621956 | 0.82 | PGR (0.52) | PGRADAMTS5ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL29622100 | 0.79 | PGR (0.43) | PGRPDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116802176-A | Oxindoles and methods of use thereof | 阿利戈斯治疗公司 | 2023-09-22 | — | — | CN | disclosed |
| EP-4240722-A1 | OXINDOLES AND METHODS OF USE THEREOF | Aligos Therapeutics, Inc. (US) | 2023-09-13 | — | — | EP | disclosed |
| WO-2022099066-A1 | OXINDOLES AND METHODS OF USE THEREOF | ALIGOS THERAPEUTICS, INC. (US) | 2022-05-12 | — | — | WO | disclosed |