Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 4/20 | 0.38 |
| ▸ | IP6K1 | Q92551 | 6/20 | 0.33 |
| ▸ | MET | P08581 | 3/20 | 0.31 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.30 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.30 |
| ▸ | AXL | P30530 | 1/20 | 0.30 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29622001 | 0.88 | PGR (0.36) | PGRIP6K1MET | |
| SCHEMBL29621882 | 0.88 | IP6K1 (0.40) | PGRIP6K1METAXLALK | |
| SCHEMBL29621848 | 0.84 | PGR (0.36) | PGRIP6K1 | |
| SCHEMBL29621974 | 0.83 | PGR (0.39) | PGRIP6K1 | |
| SCHEMBL29622045 | 0.83 | PGR (0.39) | PGRIP6K1METAXLALK | |
| SCHEMBL29621897 | 0.83 | PGR (0.41) | PGR | |
| SCHEMBL24424354 | 0.79 | THRB (0.52) | MET | |
| SCHEMBL28530057 | 0.77 | PGR (0.46) | PGRIP6K1IP6K3IP6K2 | |
| SCHEMBL29622021 | 0.77 | PGR (0.46) | PGRIP6K1IP6K3IP6K2 | |
| SCHEMBL29076792 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4240722-A1 | OXINDOLES AND METHODS OF USE THEREOF | Aligos Therapeutics, Inc. (US) | 2023-09-13 | — | — | EP | disclosed |
| WO-2022099066-A1 | OXINDOLES AND METHODS OF USE THEREOF | ALIGOS THERAPEUTICS, INC. (US) | 2022-05-12 | — | — | WO | disclosed |