Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 2/20 | 0.53 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.49 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.49 |
| ▸ | PGR | P06401 | 8/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.37 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.36 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29709557 | 0.87 | PDE7A (0.47) | PDE7ACNR1HTTGPR35GPR55 | |
| SCHEMBL20066133 | 0.87 | PDE7A (0.47) | PDE7ACNR1HTTGPR35GPR55 | |
| SCHEMBL4716029 | 0.79 | PDE7A (0.53) | PDE7APGRCA12CA1CA2 | |
| SCHEMBL29622022 | 0.77 | CNR1 (0.40) | PDE7ACNR1HTTGPR35GPR55 | |
| SCHEMBL16849927 | 0.77 | KMT2A (0.39) | PDE7ACNR1HTTGPR35GPR55 | |
| SCHEMBL4717341 | 0.76 | PDE7A (0.56) | PDE7APGR | |
| SCHEMBL4720372 | 0.75 | PDE7A (0.59) | PDE7APGRDAO | |
| SCHEMBL4078896 | 0.75 | PDE7A (0.59) | PDE7APGR | |
| SCHEMBL2264510 | 0.74 | PDK2 (0.62) | PDE7ACNR1HTTGPR35GPR55 | |
| SCHEMBL29076873 | 0.74 | PGR (0.46) | PDE7APGRCREBBPMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4240722-A1 | OXINDOLES AND METHODS OF USE THEREOF | Aligos Therapeutics, Inc. (US) | 2023-09-13 | — | — | EP | disclosed |
| WO-2022099066-A1 | OXINDOLES AND METHODS OF USE THEREOF | ALIGOS THERAPEUTICS, INC. (US) | 2022-05-12 | — | — | WO | disclosed |