Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 3/20 | 0.96 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.96 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.96 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.96 |
| ▸ | PRKCI | P41743 | 1/20 | 0.96 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.96 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | CDK2 | P24941 | 1/20 | 0.48 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phthalazinone SCHEMBL51553 | 0.98 | PARP1 (1.00) | PARP1HSD17B10TDP1ALDH1A1PRKCI | |
| Phthalazinone SCHEMBL11516875 | 0.96 | PARP1 (0.96) | PARP1HSD17B10TDP1ALDH1A1PRKCI | |
| Phthalazinone SCHEMBL2473799 | 0.96 | PARP1 (0.96) | PARP1HSD17B10TDP1ALDH1A1PRKCI | |
| Phthalazinone SCHEMBL11519239 | 0.96 | PARP1 (0.96) | PARP1HSD17B10TDP1ALDH1A1PRKCI | |
| Phthalazinone SCHEMBL9617397 | 0.96 | PARP1 (0.96) | PARP1HSD17B10TDP1ALDH1A1PRKCI | |
| Phthalazinone SCHEMBL11519244 | 0.96 | PARP1 (0.96) | PARP1HSD17B10TDP1ALDH1A1PRKCI | |
| Phthalazinone SCHEMBL11690359 | 0.96 | PARP1 (0.96) | PARP1HSD17B10TDP1ALDH1A1PRKCI | |
| Phthalazinone SCHEMBL11516881 | 0.96 | PARP1 (0.96) | PARP1HSD17B10TDP1ALDH1A1PRKCI | |
| Phthalazinone SCHEMBL4663241 | 0.96 | PARP1 (0.96) | PARP1HSD17B10TDP1ALDH1A1PRKCI | |
| Phthalazinone SCHEMBL29438173 | 0.96 | PARP1 (0.96) | PARP1HSD17B10TDP1ALDH1A1PRKCI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7759488-B2 | Monoazole ligand platinum analogs | BIONUMERIK PHARMACEUTICALS, INC. (US) | 2010-07-20 | — | — | US | claimed |
| US-7759488-B2 | Monoazole ligand platinum analogs | BIONUMERIK PHARMACEUTICALS, INC. (US) | 2010-07-20 | — | — | US | disclosed |
| US-20070004696-A1 | cis-aminedichloro [1-(phenylsulfonyl)-1H-benzotriazole] platinum for complexing with DNA and/or RNA | BIONUMERIK PHARMACEUTICALS, INC. | 2007-01-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070004696-A1 | cis-aminedichloro [1-(phenylsulfonyl)-1H-benzotriazole] platinum for complexing with DNA and/or RNA | POLRMT, LUC7L2, NSUN3 | PARP1 241/4885HSD17B10 2799/4885TDP1 1185/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.