Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.39 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.37 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2960861 | 0.86 | PPARD (0.44) | FAAH | |
| SCHEMBL27845148 | 0.82 | LPAR3 (0.50) | FAAHLPAR3LPAR2TRPM8LPAR1 | |
| SCHEMBL1295942 | 0.82 | LPAR3 (0.50) | FAAHLPAR3LPAR2TRPM8LPAR1 | |
| SCHEMBL2954338 | 0.82 | LPAR3 (0.39) | FAAHLPAR3LPAR2 | |
| SCHEMBL11466053 | 0.81 | FAAH (0.53) | FAAHLPAR3LPAR2 | |
| SCHEMBL11094630 | 0.81 | FAAH (0.53) | FAAHLPAR3LPAR2 | |
| SCHEMBL27826147 | 0.79 | LPAR3 (0.46) | FAAHLPAR3LPAR2TRPM8LPAR1 | |
| SCHEMBL27487572 | 0.79 | LPAR3 (0.46) | FAAHLPAR3LPAR2TRPM8LPAR1 | |
| SCHEMBL27845149 | 0.79 | LPAR3 (0.46) | FAAHLPAR3LPAR2TRPM8LPAR1 | |
| SCHEMBL28857705 | 0.77 | LPAR3 (0.45) | FAAHLPAR3LPAR2TRPM8LPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7754200-B2 | Phosphate transport inhibitors | GENZYME CORPORATION (US) | 2010-07-13 | — | — | US | disclosed |
| US-7754200-B2 | Phosphate transport inhibitors | GENZYME CORPORATION (US) | 2010-07-13 | — | — | US | disclosed |
| US-7754200-B2 | Phosphate transport inhibitors | GENZYME CORPORATION (US) | 2010-07-13 | — | — | US | disclosed |
| US-20060280719-A1 | Phosphate transport inhibitors | JOZEFIAK THOMAS H | 2006-12-14 | — | — | US | disclosed |
| US-7109184-B2 | Phosphate transport inhibitors | GENZYME CORPORATION (US) | 2006-09-19 | — | — | US | disclosed |
| EP-1485391-B1 | PHOSPHATE TRANSPORT INHIBITORS | GENZYME CORP (US) | 2006-08-23 | — | — | EP | disclosed |
| EP-1485391-A2 | PHOSPHATE TRANSPORT INHIBITORS | GENZYME CORPORATION (US) | 2004-12-15 | — | — | EP | disclosed |
| WO-2004085448-A2 | UNSATURATED PHOSPHINYL-PHOSPHONATE PHOSPHATE TRANSPORT INHIBITORS | GENZYME CORPORATION (US) | 2004-10-07 | — | — | WO | disclosed |
| US-20040019020-A1 | Phosphate transport inhibitors | GELTEX PHARMACEUTICALS, INC. | 2004-01-29 | — | — | US | disclosed |
| WO-2003080630-A2 | PHOSPHATE TRANSPORT INHIBITORS | GENZYME CORPORATION (US) | 2003-10-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060280719-A1 | Phosphate transport inhibitors | SLC34A2, SLC34A1, SLC43A1 | FAAH 4377/4885LPAR3 1651/4885LPAR2 1433/4885 |
| US-20040019020-A1 | Phosphate transport inhibitors | SLC34A2, SLC43A1, SLC34A1 | FAAH 4045/4885LPAR3 2860/4885LPAR2 2181/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.