Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | GFER | P55789 | 1/20 | 0.63 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | THRB | P10828 | 3/20 | 0.61 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.61 |
| ▸ | RECQL | P46063 | 2/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | APEX1 | P27695 | 1/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
| ▸ | GLA | P06280 | 1/20 | 0.59 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | CDC25B | P30305 | 1/20 | 0.57 |
| ▸ | CASP6 | P55212 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27682200 | 1.00 | KDM4E (0.63) | KDM4EKMT2AGFERRXFP1TDP1 | |
| SCHEMBL145394 | 1.00 | KDM4E (0.63) | KDM4EKMT2AGFERRXFP1TDP1 | |
| Ammonia Solution, Strong SCHEMBL2316519 | 0.98 | KDM4E (0.61) | KDM4EKMT2AGFERRXFP1TDP1 | |
| SCHEMBL688910 | 0.83 | IKBKB (0.53) | KDM4EKMT2AGFERRXFP1TDP1 | |
| SCHEMBL164836 | 0.83 | ALDH1A1 (0.53) | KDM4EKMT2AGFERRXFP1TDP1 | |
| SCHEMBL9117926 | 0.81 | KDM4E (0.44) | KDM4EKMT2AGFERRXFP1TDP1 | |
| SCHEMBL2327264 | 0.81 | KDM4E (0.41) | KDM4EKMT2AGFERRXFP1TDP1 | |
| SCHEMBL29980197 | 0.80 | MAPT (0.64) | KDM4EKMT2ATDP1MAPTMEN1 | |
| SCHEMBL1877051 | 0.80 | MAPT (0.64) | KDM4EKMT2ATDP1MAPTMEN1 | |
| SCHEMBL522679 | 0.79 | PTPN1 (0.55) | KDM4EKMT2ATDP1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4021504-A1 | THERAPY | Vestlandets Innovasjonsselskap AS (NO) | 2022-07-06 | — | — | EP | disclosed |
| EP-4013440-A1 | THERAPEUTIC PEPTIDES | Cohbar Inc. (US) | 2022-06-22 | — | — | EP | disclosed |