Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | GFER | P55789 | 1/20 | 0.63 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | THRB | P10828 | 3/20 | 0.61 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.61 |
| ▸ | RECQL | P46063 | 2/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | APEX1 | P27695 | 1/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
| ▸ | GLA | P06280 | 1/20 | 0.59 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | CDC25B | P30305 | 1/20 | 0.57 |
| ▸ | CASP6 | P55212 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27682200 | 1.00 | KDM4E (0.63) | KDM4EKMT2AGFERRXFP1TDP1 | |
| SCHEMBL29622706 | 1.00 | KDM4E (0.63) | KDM4EKMT2AGFERRXFP1TDP1 | |
| Ammonia Solution, Strong SCHEMBL2316519 | 0.98 | KDM4E (0.61) | KDM4EKMT2AGFERRXFP1TDP1 | |
| SCHEMBL688910 | 0.83 | IKBKB (0.53) | KDM4EKMT2AGFERRXFP1TDP1 | |
| SCHEMBL164836 | 0.83 | ALDH1A1 (0.53) | KDM4EKMT2AGFERRXFP1TDP1 | |
| SCHEMBL9117926 | 0.81 | KDM4E (0.44) | KDM4EKMT2AGFERRXFP1TDP1 | |
| SCHEMBL2327264 | 0.81 | KDM4E (0.41) | KDM4EKMT2AGFERRXFP1TDP1 | |
| SCHEMBL29980197 | 0.80 | MAPT (0.64) | KDM4EKMT2ATDP1MAPTMEN1 | |
| SCHEMBL1877051 | 0.80 | MAPT (0.64) | KDM4EKMT2ATDP1MAPTMEN1 | |
| SCHEMBL522679 | 0.79 | PTPN1 (0.55) | KDM4EKMT2ATDP1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1139 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118184679-A | Photothermal agent and preparation method thereof, photothermal nanoparticle and preparation method thereof, insulating material and self-repairing method of insulating material | 中国石油天然气股份有限公司 | 2024-06-14 | — | — | CN | claimed |
| CN-115010671-B | One-step synthesis method of 2-substituted quinazolinone | 江苏大学 | 2023-10-10 | — | — | CN | claimed |
| CN-115010671-A | One-step synthesis method of 2-substituted quinazolinone | 江苏大学 | 2022-09-06 | — | — | CN | claimed |
| CN-112276412-A | Laser welding solder paste and preparation method thereof | 苏州恩斯泰金属科技有限公司 | 2021-01-29 | — | — | CN | claimed |
| CN-111072576-A | Preparation method of lapatinib key intermediate | 南京奇可药业有限公司 | 2020-04-28 | — | — | CN | claimed |
| CN-106317026-B | A kind of compound being able to suppress ErbB/HDAC and preparation method thereof includes its pharmaceutical composition and application thereof | 清华大学深圳研究生院 | 2019-03-22 | — | — | CN | claimed |
| CN-105111193-B | A kind of preparation method of Lapatinib | 山东罗欣药业集团股份有限公司 | 2018-03-06 | — | — | CN | claimed |
| CN-104070307-B | Solder flux composition and solder composition | 株式会社田村制作所 | 2018-02-23 | — | — | CN | claimed |
| CN-106986895-A | Quinazoline ditosylate salt Mutiple Targets antitumoral compounds and its preparation method and application | 北京大学 | 2017-07-28 | — | — | CN | claimed |
| CN-106317026-A | Compounds capable of inhibiting ErbB/HDAC and preparation method thereof, and pharmaceutical composition comprising compounds and application thereof | 清华大学深圳研究生院 | 2017-01-11 | — | — | CN | claimed |
| CN-101001830-A | Method for producing 2-amino-5-iodobenzoic acid | MITSUBISHI GAS CHEMICAL CO (JP) | 2007-07-18 | — | — | CN | claimed |
| EP-1777215-A1 | METHOD FOR PRODUCING 2-AMINO-5-IODOBENZOIC ACID | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2007-04-25 | — | — | EP | claimed |
| EP-1344775-B1 | Preparation of fungicidal quinazolinones and useful intermediates | DU PONT (US) | 2006-11-29 | — | — | EP | claimed |
| US-20060111405-A1 | O-pyridinequinone derivatives, the composition containing the derivatives, the process for preparation of the derivatives and the use of the derivatives | GU LIANQUAN | 2006-05-25 | — | — | US | claimed |
| EP-1344775-A1 | Preparation of fungicidal quinazolinones and useful intermediates | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2003-09-17 | — | — | EP | claimed |
| US-6166208-A | Preparation of fungicidal quinazolinones and useful intermediates | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-12-26 | — | — | US | claimed |
| EP-0922037-A1 | PREPARATION OF FUNGICIDAL QUINAZOLINONES AND USEFUL INTERMEDIATES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-06-16 | — | — | EP | claimed |
| WO-1997048684-A1 | PREPARATION OF FUNGICIDAL QUINAZOLINONES AND USEFUL INTERMEDIATES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-12-24 | — | — | WO | claimed |
| EP-0070198-B1 | RADIATION-SENSITIVE COMPOSITION AND PATTERN-FORMATION METHOD USING THE SAME | Hitachi, Ltd. (JP) | 1985-06-19 | — | — | EP | claimed |
| EP-0070198-A1 | Radiation-sensitive composition and pattern-formation method using the same | Hitachi, Ltd. (JP) | 1983-01-19 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060111405-A1 | O-pyridinequinone derivatives, the composition containing the derivatives, the process for preparation of the derivatives and the use of the derivatives | PTGS2, PTGES2, PTGES | KDM4E 1317/4885KMT2A 2390/4885GFER 1745/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.