Golotimod

Golotimod

SCHEMBL29622906

NC(CCC(=O)NC(Cc1c[nH]c2ccccc12)C(=O)O)C(=O)O

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.65
MEN1 O00255 1/20 0.65
LMNA P02545 1/20 0.65
MPO P05164 1/20 0.65
MAPT P10636 1/20 0.65
TSHR P16473 1/20 0.65
BLM P54132 1/20 0.65
PMP22 Q01453 1/20 0.65
KMT2A Q03164 1/20 0.65
HIF1A Q16665 1/20 0.65
ERAP2 Q6P179 2/20 0.62
ALOX15 P16050 1/20 0.61
ACE P12821 4/20 0.61
ITGB2 P05107 4/20 0.60
ICAM1 P05362 4/20 0.60
ITGAL P20701 4/20 0.60
PPARG P37231 1/20 0.59
P2RY14 Q15391 1/20 0.59
TP53 P04637 1/20 0.59
POLB P06746 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Golotimod SCHEMBL14790029 1.00 KDM4E (0.65) KDM4EMEN1LMNAMPOMAPT
Golotimod SCHEMBL12966340 1.00 KDM4E (0.65) KDM4EMEN1LMNAMPOMAPT
Golotimod SCHEMBL727944 1.00 KDM4E (0.65) KDM4EMEN1LMNAMPOMAPT
Golotimod SCHEMBL1768729 1.00 KDM4E (0.65) KDM4EMEN1LMNAMPOMAPT
Orilotimod SCHEMBL733964 1.00 KDM4E (0.65) KDM4EMEN1LMNAMPOMAPT
Golotimod SCHEMBL726291 1.00 KDM4E (0.65) KDM4EMEN1LMNAMPOMAPT
Golotimod SCHEMBL12818886 1.00 KDM4E (0.65) KDM4EMEN1LMNAMPOMAPT
Golotimod SCHEMBL726938 1.00 KDM4E (0.65) KDM4EMEN1LMNAMPOMAPT
Orilotimod SCHEMBL29379690 1.00 KDM4E (0.65) KDM4EMEN1LMNAMPOMAPT
SCHEMBL645413 0.93 ERAP2 (0.60) KDM4EMEN1LMNAMPOMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113330022-B Peptides having antioxidant activity and compositions comprising the same 泉标食品有限公司 2025-03-11 CN disclosed