Golotimod

Golotimod

SCHEMBL727944

N[C@H](CCC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)O)C(=O)O

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.65
MEN1 O00255 1/20 0.65
LMNA P02545 1/20 0.65
MPO P05164 1/20 0.65
MAPT P10636 1/20 0.65
TSHR P16473 1/20 0.65
BLM P54132 1/20 0.65
PMP22 Q01453 1/20 0.65
KMT2A Q03164 1/20 0.65
HIF1A Q16665 1/20 0.65
ERAP2 Q6P179 2/20 0.62
ALOX15 P16050 1/20 0.61
ACE P12821 4/20 0.61
ITGB2 P05107 4/20 0.60
ICAM1 P05362 4/20 0.60
ITGAL P20701 4/20 0.60
PPARG P37231 1/20 0.59
P2RY14 Q15391 1/20 0.59
TP53 P04637 1/20 0.59
POLB P06746 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Golotimod SCHEMBL14790029 1.00 KDM4E (0.65) KDM4EMEN1LMNAMPOMAPT
Golotimod SCHEMBL12966340 1.00 KDM4E (0.65) KDM4EMEN1LMNAMPOMAPT
Golotimod SCHEMBL1768729 1.00 KDM4E (0.65) KDM4EMEN1LMNAMPOMAPT
Orilotimod SCHEMBL733964 1.00 KDM4E (0.65) KDM4EMEN1LMNAMPOMAPT
Golotimod SCHEMBL726291 1.00 KDM4E (0.65) KDM4EMEN1LMNAMPOMAPT
Golotimod SCHEMBL12818886 1.00 KDM4E (0.65) KDM4EMEN1LMNAMPOMAPT
Golotimod SCHEMBL29622906 1.00 KDM4E (0.65) KDM4EMEN1LMNAMPOMAPT
Golotimod SCHEMBL726938 1.00 KDM4E (0.65) KDM4EMEN1LMNAMPOMAPT
Orilotimod SCHEMBL29379690 1.00 KDM4E (0.65) KDM4EMEN1LMNAMPOMAPT
SCHEMBL645413 0.93 ERAP2 (0.60) KDM4EMEN1LMNAMPOMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 397 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12548678-B2 Methods and systems for machine learning analysis of single nucleotide polymorphisms in lupus AMPEL BIOSOLUTIONS, LLC (US) 2026-02-10 US claimed
WO-2025111482-A1 COMPLEXING AGENT SALT FORMULATIONS OF PHARMACEUTICAL COMPOUNDS AT LOW STOICHIOMETRIC RATIOS BEXSON BIOMEDICAL, INC. (US) 2025-05-30 WO claimed
CN-117070570-A Method for improving transfection efficiency of liposome transfection reagent 南通大学 2023-11-17 CN claimed
US-11583544-B2 Remote loading of sparingly water-soluble drugs into lipid vesicles CELATOR PHARMACEUTICALS, INC. (US) 2023-02-21 US claimed
US-10760129-B2 Th17 differentiation markers for acne and uses thereof GALDERMA RESEARCH & DEVELOPMENT (FR) 2020-09-01 US claimed
US-20170368081-A1 METHOD FOR TREATING RECURRING SKIN AND MUCOUS MEMBRANE DISEASES CAUSED BY HSV-1 AND HSV-2 Tets, Viktor Veniaminovich (RU) 2017-12-28 US claimed
US-20140235475-A1 TH17 DIFFERENTIATION MARKERS FOR ACNE AND USES THEREOF GALDERMA RESEARCH & DEVELOPMENT (FR) 2014-08-21 US claimed
US-20140221231-A1 TH-17 DIFFERENTIATION MARKERS FOR ROSACEA AND USES THEREOF GALDERMA RESEARCH & DEVELOPMENT (FR) 2014-08-07 US claimed
EP-2723890-A1 NEW TH17 DIFFERENTIATION MARKERS FOR ACNE AND USES THEREOF Galderma Research & Development (FR) 2014-04-30 EP claimed
EP-2723889-A1 NEW TH17 DIFFERENTIATION MARKERS FOR ACNE AND USES THEREOF Galderma Research & Development (FR) 2014-04-30 EP claimed
EP-2078525-A2 Treatment of tuberculosis using immunomodulator compounds SciClone Pharmaceuticals, Inc. (US) 2009-07-15 EP claimed
US-7173013-B2 Treatment of tuberculosis using immunomodulator compounds SCICLONE PHARMACEUTICALS, INC. (US) 2007-02-06 US claimed
EP-1420808-A4 TREATMENT OF TUBERCULOSIS USING IMMUNOMODULATOR COMPOUNDS SCICLONE PHARMACEUTICALS INC (US) 2006-06-07 EP claimed
US-20040259806-A1 Treatment of tuberculosis using immunomodulator compounds SCICLONE PHARMACEUTICALS, INC. 2004-12-23 US claimed
JP-2004537579-A 2004-12-16 JP claimed
CN-1155571-C Gamma-glutamyl and beta-aspartyl containing immunomodulator compounds and methods of making the same ������������ҩ�������ι�˾ 2004-06-30 CN claimed
EP-1420808-A1 TREATMENT OF TUBERCULOSIS USING IMMUNOMODULATOR COMPOUNDS Sciclone Pharmaceuticals, Inc. (US) 2004-05-26 EP claimed
WO-2003013572-A1 TREATMENT OF TUBERCULOSIS USING IMMUNOMODULATOR COMPOUNDS SCICLONE PHARMACEUTICALS, INC. (US) 2003-02-20 WO claimed
CN-1284943-A Gamma-glutamyl and beta-aspartyl containing immunomodulator compounds and methods of making the same WEI EDWARD T (US) 2001-02-21 CN claimed
US-5916878-A DIPEPTIDE OF EITHER GAMMA-GLUTAMYL-L-TRYPTOPHAN OR BETA-ASPARTYL-L-TRYPTOPHAN; ADMINISTERING TO THE PATIENTS TO REDUCE THE RISKS INFECTIONS FROM MICROORGANISM Wei, Edward T. (US) 1999-06-29 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170368081-A1 METHOD FOR TREATING RECURRING SKIN AND MUCOUS MEMBRANE DISEASES CAUSED BY HSV-1 AND HSV-2 PMP22, CUTA, HRH2 KDM4E 1348/4885MEN1 757/4885LMNA 2929/4885
US-20040259806-A1 Treatment of tuberculosis using immunomodulator compounds IFNG, IFNAR1, CD4 KDM4E 4329/4885MEN1 2589/4885LMNA 4275/4885
US-12548678-B2 Methods and systems for machine learning analysis of single nucleotide polymorphisms in lupus SSB, METTL16, TLR9 KDM4E 2934/4885MEN1 4189/4885LMNA 461/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.