Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 2/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
| ▸ | TUBB | P07437 | 1/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.38 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.38 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.38 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.38 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.38 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.38 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.38 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.38 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.38 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24090108 | 1.00 | ACP1 (0.39) | ACP1JAK2SYKTUBB4ATUBB | |
| SCHEMBL24089967 | 0.90 | TDO2 (0.41) | JAK2SYK | |
| SCHEMBL29623066 | 0.88 | NPC1 (0.40) | ACP1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL29623137 | 0.88 | ACP1 (0.40) | ACP1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL23045336 | 0.88 | ACP1 (0.40) | ACP1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL23045335 | 0.88 | NPC1 (0.40) | ACP1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL23064457 | 0.87 | MAT2A (0.41) | SMN1; SMN2 | |
| SCHEMBL29623222 | 0.86 | KMT2A (0.47) | ACP1JAK2SYKMEN1KMT2A | |
| SCHEMBL24089977 | 0.86 | KMT2A (0.47) | ACP1JAK2SYKMEN1KMT2A | |
| SCHEMBL23065073 | 0.85 | ACP1 (0.48) | ACP1AVPR1BSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114650986-A | 2-aminoquinazolinone derivatives | 住友制药株式会社 | 2022-06-21 | — | — | CN | claimed |
| CN-114650986-A | 2-aminoquinazolinone derivatives | 住友制药株式会社 | 2022-06-21 | — | — | CN | disclosed |