Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | MAT2A | P31153 | 1/20 | 0.41 |
| ▸ | JUN | P05412 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24089920 | 1.00 | PRMT5 (0.41) | PRMT5CYP1A2MAT2AJUNNFKB1 | |
| SCHEMBL23065069 | 0.91 | MAT2A (0.45) | PRMT5CYP1A2MAT2A | |
| SCHEMBL29746906 | 0.91 | MAT2A (0.45) | PRMT5CYP1A2MAT2A | |
| SCHEMBL29623309 | 0.90 | ACP1 (0.48) | PRMT5MAT2AJUNNFKB1NFKB2 | |
| SCHEMBL23045341 | 0.90 | ACP1 (0.48) | PRMT5MAT2AJUNNFKB1NFKB2 | |
| SCHEMBL24089957 | 0.88 | TDO2 (0.41) | — | |
| SCHEMBL29623225 | 0.86 | KDM4E (0.44) | — | |
| SCHEMBL23045330 | 0.86 | KDM4E (0.44) | — | |
| SCHEMBL24090094 | 0.85 | TP53 (0.48) | JUNNFKB1NFKB2RELANPC1 | |
| SCHEMBL29623326 | 0.85 | TP53 (0.48) | JUNNFKB1NFKB2RELANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114650986-A | 2-aminoquinazolinone derivatives | 住友制药株式会社 | 2022-06-21 | — | — | CN | claimed |
| CN-114650986-A | 2-aminoquinazolinone derivatives | 住友制药株式会社 | 2022-06-21 | — | — | CN | disclosed |